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Study · Animal study (in vivo) · rat · 2009

6 results

Abdominal aorta anastomosis in rats and stable gastric pentadecapeptide BPC 157, prophylaxis and therapy.

Hrelec M, Klicek R, Brcic L, Brcic I, Cvjetko I, Seiwerth S, Sikiric P

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society1 Dec 2009Cited by 36 (Europe PMC)

PMID20388960 (opens in a new tab)PepBankPUB-20388960
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study6

6 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats after aortic termino-terminal anastomosis, BPC‑157 given as a bath immediately after surgery decreased clot formation.

    In plain wordsIn rats after aortic surgery, a BPC‑157 bath given right after surgery reduced clot formation.

    Peptide
    BPC-157
    Outcome
    DecreaseClot formation after aortic anastomosis (bath, prophylaxis)
    Study

    ratn: not reported in source

    Abdominal aorta termino-terminal anastomosis
    Outcome group
    Cardiovascular events · Cardiovascular
    Studied dose
    10 microg/kg · bathAs given in this study (rat).

    Source sentences

    Summary
    After 24 h following aortic termino-terminal anastomosis, we shown that BPC 157 (10 microg/kg) may also decrease formation of cloth after aortic termino-terminal anastomosis and preserved walking ability and muscle strength when given as a bath immediately after aortic anastomosis creation.
    1 context sentence
    Summary · context
    We focused on abdominal aorta, clamped and transected bellow renal arteries, and aortic termino-terminal anastomosis created in Albino male rats.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats after aortic termino-terminal anastomosis, BPC‑157 given as a bath immediately after surgery preserved walking ability.

    In plain wordsIn rats after aortic surgery, a BPC‑157 bath given right after surgery kept walking ability.

    Peptide
    BPC-157
    Outcome
    IncreaseWalking ability after aortic anastomosis (bath, prophylaxis)
    Study

    ratn: not reported in source

    Abdominal aorta termino-terminal anastomosis
    Outcome group
    Exercise and physical function · Musculoskeletal
    Studied dose
    10 microg/kg · bathAs given in this study (rat).

    Source sentences

    Summary
    After 24 h following aortic termino-terminal anastomosis, we shown that BPC 157 (10 microg/kg) may also decrease formation of cloth after aortic termino-terminal anastomosis and preserved walking ability and muscle strength when given as a bath immediately after aortic anastomosis creation.
    1 context sentence
    Summary · context
    We focused on abdominal aorta, clamped and transected bellow renal arteries, and aortic termino-terminal anastomosis created in Albino male rats.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In rats after aortic termino-terminal anastomosis, BPC‑157 given as a bath immediately after surgery preserved muscle strength.

    In plain wordsIn rats after aortic surgery, a BPC‑157 bath given right after surgery kept muscle strength.

    Peptide
    BPC-157
    Outcome
    IncreaseMuscle strength after aortic anastomosis (bath, prophylaxis)
    Study

    ratn: not reported in source

    Abdominal aorta termino-terminal anastomosis
    Outcome group
    Exercise and physical function · Musculoskeletal
    Studied dose
    10 microg/kg · bathAs given in this study (rat).

    Source sentences

    Summary
    After 24 h following aortic termino-terminal anastomosis, we shown that BPC 157 (10 microg/kg) may also decrease formation of cloth after aortic termino-terminal anastomosis and preserved walking ability and muscle strength when given as a bath immediately after aortic anastomosis creation.
    1 context sentence
    Summary · context
    We focused on abdominal aorta, clamped and transected bellow renal arteries, and aortic termino-terminal anastomosis created in Albino male rats.
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In rats 24 h after aortic termino-terminal anastomosis, intraperitoneal BPC‑157 rapidly recovered the function of the lower limbs within 3 minutes.

    In plain wordsIn rats 24 hours after aortic surgery, BPC‑157 injected into the abdomen quickly restored leg function.

    Peptide
    BPC-157
    Outcome
    IncreaseLower limb function recovery 24 h after anastomosis (therapy)
    Study

    ratn: not reported in source

    Abdominal aorta termino-terminal anastomosis
    Outcome group
    Exercise and physical function · Musculoskeletal
    Studied dose
    10 microg/kg · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    Given at the that point, intraperitoneally, within 3 minutes post-application interval the pentadecapeptide BPC 157 rapidly recovered the function of lower limbs and muscle strength while no cloth could be seen in those rats at the anastomosis site.
    1 context sentence
    Summary · context
    We focused on abdominal aorta, clamped and transected bellow renal arteries, and aortic termino-terminal anastomosis created in Albino male rats.
  5. 05AnimalAnimal study (in vivo)Efficacy outcome

    In rats 24 h after aortic termino-terminal anastomosis, intraperitoneal BPC‑157 rapidly recovered muscle strength within 3 minutes.

    In plain wordsIn rats 24 hours after aortic surgery, BPC‑157 injected into the abdomen quickly restored muscle strength.

    Peptide
    BPC-157
    Outcome
    IncreaseMuscle strength recovery 24 h after anastomosis (therapy)
    Study

    ratn: not reported in source

    Abdominal aorta termino-terminal anastomosis
    Outcome group
    Exercise and physical function · Musculoskeletal
    Studied dose
    10 microg/kg · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    Given at the that point, intraperitoneally, within 3 minutes post-application interval the pentadecapeptide BPC 157 rapidly recovered the function of lower limbs and muscle strength while no cloth could be seen in those rats at the anastomosis site.
    1 context sentence
    Summary · context
    We focused on abdominal aorta, clamped and transected bellow renal arteries, and aortic termino-terminal anastomosis created in Albino male rats.
  6. 06AnimalAnimal study (in vivo)Efficacy outcome

    In rats 24 h after aortic termino-terminal anastomosis, no clot could be seen at the anastomosis site after intraperitoneal BPC‑157.

    In plain wordsIn rats 24 hours after aortic surgery, no clot could be seen at the join after BPC‑157 was injected.

    Peptide
    BPC-157
    Outcome
    DecreaseClot at anastomosis site 24 h after surgery (therapy)
    Study

    ratn: not reported in source

    Abdominal aorta termino-terminal anastomosis
    Outcome group
    Cardiovascular events · Cardiovascular
    Studied dose
    10 microg/kg · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    Given at the that point, intraperitoneally, within 3 minutes post-application interval the pentadecapeptide BPC 157 rapidly recovered the function of lower limbs and muscle strength while no cloth could be seen in those rats at the anastomosis site.
    1 context sentence
    Summary · context
    We focused on abdominal aorta, clamped and transected bellow renal arteries, and aortic termino-terminal anastomosis created in Albino male rats.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:56 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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