The effects of Kisspeptin antibodies on delayed estrus in rats.

Risvanli A, Apaydin AM, Bulut H, Timurkaan N, Saat N

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology1 Apr 2010Cited by 2 (Europe PMC)

PMID20222841DOI10.3109/09513590903367044PepBankPUB-20222841

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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study7

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone7

In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Kisspeptin-10.

01AnimalNot a test of Kisspeptin-10 aloneAnimal study (in vivo)Other
In female rats given antibodies against kisspeptin‑10, the number of estrous cycles did not differ from control rats.
In plain wordsIn rats given antibodies against kisspeptin‑10, the number of estrous cycles was the same as in controls.
Peptide
Kisspeptin-10
Outcome
No significant changeNumber of estrous cycles
Study
ratn = 10
Comparator
Control rats
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
However, no difference was found between the groups with regard to the number of estrous cycles observed, the interval between estrous periods, estradiol concentrations, the number of follicles and corpora lutea and immunohistochemical results.
1 context sentence(design, population, supporting numbers)
Summary · context
To this end, five Wistar female rats were passively immunised using a hyperimmune serum obtained from two Wistar female rats against Kisspeptin 10.
In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-10.
Report a problemFND-2022284102
02AnimalNot a test of Kisspeptin-10 aloneAnimal study (in vivo)Other
In female rats given antibodies against kisspeptin‑10, the interval between estrous periods did not differ from control rats.
In plain wordsIn rats given antibodies against kisspeptin‑10, the time between estrous periods was the same as in controls.
Peptide
Kisspeptin-10
Outcome
No significant changeInterval between estrous periods
Study
ratn = 10
Comparator
Control rats
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
However, no difference was found between the groups with regard to the number of estrous cycles observed, the interval between estrous periods, estradiol concentrations, the number of follicles and corpora lutea and immunohistochemical results.
1 context sentence(design, population, supporting numbers)
Summary · context
To this end, five Wistar female rats were passively immunised using a hyperimmune serum obtained from two Wistar female rats against Kisspeptin 10.
In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-10.
Report a problemFND-2022284103
03AnimalNot a test of Kisspeptin-10 aloneAnimal study (in vivo)Other
In female rats given antibodies against kisspeptin‑10, estradiol concentrations did not differ from control rats.
In plain wordsIn rats given antibodies against kisspeptin‑10, estradiol levels were the same as in controls.
Peptide
Kisspeptin-10
Outcome
No significant changeBlood estradiol concentration
Study
ratn = 10
Comparator
Control rats
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
However, no difference was found between the groups with regard to the number of estrous cycles observed, the interval between estrous periods, estradiol concentrations, the number of follicles and corpora lutea and immunohistochemical results.
1 context sentence(design, population, supporting numbers)
Summary · context
To this end, five Wistar female rats were passively immunised using a hyperimmune serum obtained from two Wistar female rats against Kisspeptin 10.
In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-10.
Report a problemFND-2022284104
04AnimalNot a test of Kisspeptin-10 aloneAnimal study (in vivo)Other
In female rats given antibodies against kisspeptin‑10, the number of follicles did not differ from control rats.
In plain wordsIn rats given antibodies against kisspeptin‑10, the number of ovarian follicles was the same as in controls.
Peptide
Kisspeptin-10
Outcome
No significant changeNumber of ovarian follicles
Study
ratn = 10
Comparator
Control rats
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
However, no difference was found between the groups with regard to the number of estrous cycles observed, the interval between estrous periods, estradiol concentrations, the number of follicles and corpora lutea and immunohistochemical results.
1 context sentence(design, population, supporting numbers)
Summary · context
To this end, five Wistar female rats were passively immunised using a hyperimmune serum obtained from two Wistar female rats against Kisspeptin 10.
In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-10.
Report a problemFND-2022284105
05AnimalNot a test of Kisspeptin-10 aloneAnimal study (in vivo)Other
In female rats given antibodies against kisspeptin‑10, the number of corpora lutea did not differ from control rats.
In plain wordsIn rats given antibodies against kisspeptin‑10, the number of corpora lutea was the same as in controls.
Peptide
Kisspeptin-10
Outcome
No significant changeNumber of corpora lutea
Study
ratn = 10
Comparator
Control rats
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
However, no difference was found between the groups with regard to the number of estrous cycles observed, the interval between estrous periods, estradiol concentrations, the number of follicles and corpora lutea and immunohistochemical results.
1 context sentence(design, population, supporting numbers)
Summary · context
To this end, five Wistar female rats were passively immunised using a hyperimmune serum obtained from two Wistar female rats against Kisspeptin 10.
In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-10.
Report a problemFND-2022284106
06AnimalNot a test of Kisspeptin-10 aloneAnimal study (in vivo)Other
In female rats given antibodies against kisspeptin‑10, pituitary GnRH receptor immunohistochemical results did not differ from control rats.
In plain wordsIn rats given antibodies against kisspeptin‑10, GnRH receptor staining in the pituitary was the same as in controls.
Peptide
Kisspeptin-10
Outcome
No significant changeGnRH receptor immunohistochemistry in pituitaries
Study
ratn = 10
Comparator
Control rats
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
However, no difference was found between the groups with regard to the number of estrous cycles observed, the interval between estrous periods, estradiol concentrations, the number of follicles and corpora lutea and immunohistochemical results.
1 context sentence(design, population, supporting numbers)
Summary · context
To this end, five Wistar female rats were passively immunised using a hyperimmune serum obtained from two Wistar female rats against Kisspeptin 10.
In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-10.
Report a problemFND-2022284107
07AnimalNot a test of Kisspeptin-10 aloneAnimal study (in vivo)Other
In female rats passively immunised with a hyperimmune serum against kisspeptin‑10, strong seropositivity was detected.
In plain wordsIn rats given antibodies against kisspeptin‑10, the antibodies were detected in their blood.
Peptide
Kisspeptin-10
Outcome
Not applicableSeropositivity against kisspeptin-10 after passive immunisation
Study
ratn = 5
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
Consequently, strong seropositivity was detected in all passively immunised rats and the hyperimmune serum.
1 context sentence(design, population, supporting numbers)
Summary · context
To this end, five Wistar female rats were passively immunised using a hyperimmune serum obtained from two Wistar female rats against Kisspeptin 10.
In this study, Kisspeptin-10 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Kisspeptin-10.
Report a problemFND-2022284101

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
10 Oct 2026, 09:43 UTC
Study results updated
Version 1
9 Oct 2026, 03:04 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

Journal Article

MeSH terms

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