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Study · Randomized controlled trial · 2010

2 results

Intranasal desmopressin versus blood transfusion in cirrhotic patients with coagulopathy undergoing dental extraction: a randomized controlled trial.

Stanca CM, Montazem AH, Lawal A, Zhang JX, Schiano TD

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons1 Jan 2010Cited by 38 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanRandomized controlled trialOther

    In cirrhotic patients undergoing dental extraction, average costs were $700/patient with desmopressin versus $1,173/patient with transfusion.

    In plain wordsIn cirrhotic patients undergoing tooth extraction, desmopressin cost $700/patient versus $1,173/patient for transfusion.

    Outcome
    DecreaseTreatment-associated costs
    Study

    n: not reported in source

    Comparator
    Blood transfusion
    Outcome group
    Treatment Costs · Whole body
    Studied dose
    300 microg · intranasalAs given in this study (human).

    Measurements

    Treatment-associated average cost
    700 $/patient
    intranasal desmopressin
    Treatment-associated average cost
    1173 $/patient
    blood transfusion

    Source sentences

    Summary
    Treatment associated average costs were lower for desmopressin ($700/patient) compared with transfusion ($1,173/patient).
    2 context sentences
    Summary · context
    Cirrhotic patients with platelet counts of 30,000 to 50,000/microL and/or international normalized ratio (INR) 2.0 to 3.0 were enrolled in a prospective, controlled, randomized clinical trial.
    Summary · context
    Blood transfusion (fresh frozen plasma 10 mL/kg and/or 1 unit of single donor platelets, respectively) or intranasal desmopressin (300 microg) were given before dental extraction.
  2. 02HumanNon-randomized trialEfficacy outcome

    In cirrhotic patients undergoing dental extraction, no desmopressin recipients required rescue blood transfusion after extraction.

    In plain wordsIn cirrhotic patients undergoing tooth extraction, no desmopressin recipients needed rescue blood transfusion.

    Outcome
    Not applicableRescue blood transfusion
    Study

    n: not reported in source

    Outcome group
    Bleeding and clotting · Whole body
    Studied dose
    300 microg · intranasalAs given in this study (human).

    Source sentences

    Summary
    No patients in desmopressin group required rescue blood transfusion after extraction.
    2 context sentences
    Summary · context
    Cirrhotic patients with platelet counts of 30,000 to 50,000/microL and/or international normalized ratio (INR) 2.0 to 3.0 were enrolled in a prospective, controlled, randomized clinical trial.
    Summary · context
    Blood transfusion (fresh frozen plasma 10 mL/kg and/or 1 unit of single donor platelets, respectively) or intranasal desmopressin (300 microg) were given before dental extraction.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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