Subcutaneous gonadotropin-releasing hormone agonist (triptorelin) test for diagnosing precocious puberty.

Poomthavorn P, Khlairit P, Mahachoklertwattana P

Hormone research18 Aug 2009Cited by 40 (Europe PMC)

PMID19690429DOI10.1159/000232164PepBankPUB-19690429

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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone4

In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Triptorelin (Trelstar, Decapeptyl).

01HumanNot a test of Triptorelin (Trelstar, Decapeptyl) aloneObservational studyActivity measurement
After triptorelin testing, girls with CPP had higher peak LH than girls with premature thelarche, with medians of 10.0 versus 3.04 IU/l.
In plain wordsAfter triptorelin testing, girls with CPP had higher peak LH than girls with premature thelarche.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
IncreaseStimulated peak LH
Study
n = 101
Comparator
Premature thelarche
Outcome group
Sex hormones and fertility · Endocrine and hormones
Measurements
Peak LH, median
10 IU/l
CPP group (n=55); range 2.93-65.39
Peak LH, median
3.04 IU/l
Premature thelarche group (n=46); range 0.19-8.82
Source sentences
Summary
Peak LH concentration in the CPP group was significantly greater than that of the PT group with a median (range) of 10.0 IU/l (2.93-65.39) and 3.04 IU/l (0.19-8.82), respectively.
2 context sentences(design, population, supporting numbers)
Summary · context
A retrospective study of 101 girls with sexual precocity was undertaken.
Summary · context
All girls underwent 100 microg subcutaneous GnRH-A (triptorelin) testing.
In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).
Report a problemFND-1969042901
02HumanNot a test of Triptorelin (Trelstar, Decapeptyl) aloneObservational studyActivity measurement
In girls with sexual precocity, peak LH occurred within 60 minutes after triptorelin injection.
In plain wordsIn girls with sexual precocity, peak LH occurred within 60 minutes after triptorelin injection.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
Not applicableTime to peak LH
Study
n = 101
Outcome group
Sex hormones and fertility · Endocrine and hormones
Measurements
Time to peak LH
≤ 60 min
After subcutaneous GnRH-A injection
Source sentences
Summary
Peak LH was achieved within 60 min following GnRH-A injection.
2 context sentences(design, population, supporting numbers)
Summary · context
A retrospective study of 101 girls with sexual precocity was undertaken.
Summary · context
All girls underwent 100 microg subcutaneous GnRH-A (triptorelin) testing.
In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).
Report a problemFND-1969042902
03HumanNot a test of Triptorelin (Trelstar, Decapeptyl) aloneObservational studyOther
In girls with sexual precocity, the triptorelin test peak LH cutoff of 6 IU/l had 89.1% sensitivity for CPP.
In plain wordsIn girls with sexual precocity, the triptorelin test peak LH cutoff of 6 IU/l had 89.1% sensitivity for CPP.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
Not applicableDiagnostic sensitivity
Study
n = 101
Outcome group
Sex hormones and fertility · Endocrine and hormones
Measurements
Sensitivity
89.1%
peak LH cutoff 6 IU/l, diagnosing CPP
Source sentences
Summary
Peak LH of 6 IU/l provided the most appropriate cutoff level in diagnosing CPP with a sensitivity of 89.1% and a specificity of 91.3%.
2 context sentences(design, population, supporting numbers)
Summary · context
A retrospective study of 101 girls with sexual precocity was undertaken.
Summary · context
All girls underwent 100 microg subcutaneous GnRH-A (triptorelin) testing.
In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).
Report a problemFND-1969042903
04HumanNot a test of Triptorelin (Trelstar, Decapeptyl) aloneObservational studyOther
In girls with sexual precocity, the triptorelin test peak LH cutoff of 6 IU/l had 91.3% specificity for CPP.
In plain wordsIn girls with sexual precocity, the triptorelin test peak LH cutoff of 6 IU/l had 91.3% specificity for CPP.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
Not applicableDiagnostic specificity
Study
n = 101
Outcome group
Sex hormones and fertility · Endocrine and hormones
Measurements
Specificity
91.3%
peak LH cutoff 6 IU/l, diagnosing CPP
Source sentences
Summary
Peak LH of 6 IU/l provided the most appropriate cutoff level in diagnosing CPP with a sensitivity of 89.1% and a specificity of 91.3%.
2 context sentences(design, population, supporting numbers)
Summary · context
A retrospective study of 101 girls with sexual precocity was undertaken.
Summary · context
All girls underwent 100 microg subcutaneous GnRH-A (triptorelin) testing.
In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).
Report a problemFND-1969042904

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
22 Oct 2026, 02:26 UTC
Study results updated
Version 1
21 Oct 2026, 18:59 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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