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Study · In vitro (cells) · goldfish · 2010

8 results

Goldfish kisspeptin: molecular cloning, tissue distribution of transcript expression, and stimulatory effects on prolactin, growth hormone and luteinizing hormone secretion and gene expression via direct actions at the pituitary level.

Yang B, Jiang Q, Chan T, Ko WK, Wong AO

General and comparative endocrinology6 Jun 2009Cited by 100 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study8

6 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Efficacy outcome

    In goldfish pituitary cell cultures, 30-min incubation with goldfish kisspeptin‑10 increased basal release of luteinizing hormone.

    In plain wordsIn goldfish pituitary cells, kisspeptin‑10 raised release of luteinizing hormone within 30 minutes.

    Outcome
    IncreaseBasal LH release
    Study

    goldfishn: not reported in source

    Goldfish pituitary cell cultures
    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    Dose not stated · 30 minAs given in this study (goldfish).

    Source sentences

    Summary
    In goldfish pituitary cell cultures, 30-min incubation with kisspeptin-10 increased basal release of luteinizing hormone (LH), prolactin (PRL), and growth hormone (GH).
    1 context sentence
    Summary · context
    In parallel studies, goldfish kisspeptin-10 was synthesized and used to test the pituitary actions of kisspeptin in vitro.
  2. 02LabIn vitro (cells)Efficacy outcome

    In goldfish pituitary cell cultures, 30-min incubation with goldfish kisspeptin‑10 increased basal release of prolactin.

    In plain wordsIn goldfish pituitary cells, kisspeptin‑10 raised release of prolactin within 30 minutes.

    Outcome
    IncreaseBasal prolactin release
    Study

    goldfishn: not reported in source

    Goldfish pituitary cell cultures
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated · 30 minAs given in this study (goldfish).

    Source sentences

    Summary
    In goldfish pituitary cell cultures, 30-min incubation with kisspeptin-10 increased basal release of luteinizing hormone (LH), prolactin (PRL), and growth hormone (GH).
    1 context sentence
    Summary · context
    In parallel studies, goldfish kisspeptin-10 was synthesized and used to test the pituitary actions of kisspeptin in vitro.
  3. 03LabIn vitro (cells)Efficacy outcome

    In goldfish pituitary cell cultures, 30-min incubation with goldfish kisspeptin‑10 increased basal release of growth hormone.

    In plain wordsIn goldfish pituitary cells, kisspeptin‑10 raised release of growth hormone within 30 minutes.

    Outcome
    IncreaseBasal growth hormone release
    Study

    goldfishn: not reported in source

    Goldfish pituitary cell cultures
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated · 30 minAs given in this study (goldfish).

    Source sentences

    Summary
    In goldfish pituitary cell cultures, 30-min incubation with kisspeptin-10 increased basal release of luteinizing hormone (LH), prolactin (PRL), and growth hormone (GH).
    1 context sentence
    Summary · context
    In parallel studies, goldfish kisspeptin-10 was synthesized and used to test the pituitary actions of kisspeptin in vitro.
  4. 04LabIn vitro (cells)Efficacy outcome

    In goldfish pituitary cell cultures, 24-h kisspeptin‑10 treatment elevated LH transcript expression.

    In plain wordsIn goldfish pituitary cells, 24 hours of kisspeptin‑10 raised LH gene activity.

    Outcome
    IncreaseLH transcript expression
    Study

    goldfishn: not reported in source

    Goldfish pituitary cell cultures
    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    Dose not stated · 24 hAs given in this study (goldfish).

    Source sentences

    Summary
    Transcript expression of LH, PRL, and GH were also elevated by prolonging kisspeptin-10 treatment to 24h.
    1 context sentence
    Summary · context
    In parallel studies, goldfish kisspeptin-10 was synthesized and used to test the pituitary actions of kisspeptin in vitro.
  5. 05LabIn vitro (cells)Efficacy outcome

    In goldfish pituitary cell cultures, 24-h kisspeptin‑10 treatment elevated prolactin transcript expression.

    In plain wordsIn goldfish pituitary cells, 24 hours of kisspeptin‑10 raised prolactin gene activity.

    Outcome
    IncreaseProlactin transcript expression
    Study

    goldfishn: not reported in source

    Goldfish pituitary cell cultures
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated · 24 hAs given in this study (goldfish).

    Source sentences

    Summary
    Transcript expression of LH, PRL, and GH were also elevated by prolonging kisspeptin-10 treatment to 24h.
    1 context sentence
    Summary · context
    In parallel studies, goldfish kisspeptin-10 was synthesized and used to test the pituitary actions of kisspeptin in vitro.
  6. 06LabIn vitro (cells)Efficacy outcome

    In goldfish pituitary cell cultures, 24-h kisspeptin‑10 treatment elevated growth hormone transcript expression.

    In plain wordsIn goldfish pituitary cells, 24 hours of kisspeptin‑10 raised growth hormone gene activity.

    Outcome
    IncreaseGrowth hormone transcript expression
    Study

    goldfishn: not reported in source

    Goldfish pituitary cell cultures
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated · 24 hAs given in this study (goldfish).

    Source sentences

    Summary
    Transcript expression of LH, PRL, and GH were also elevated by prolonging kisspeptin-10 treatment to 24h.
    1 context sentence
    Summary · context
    In parallel studies, goldfish kisspeptin-10 was synthesized and used to test the pituitary actions of kisspeptin in vitro.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 07AnimalEndogenous levelAnimal study (in vivo)Other

    In goldfish, Kiss1 transcript was widely expressed in various tissues.

    In plain wordsIn goldfish, the gene for the body's own kisspeptin was active in many tissues.

    Outcome
    Not applicableKiss1 transcript tissue distribution
    Study

    goldfishn: not reported in source

    Goldfish tissues
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    Kiss1 transcript was shown to be widely expressed in various tissues in goldfish.

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

  2. 08LabEndogenous levelEx vivo tissueOther

    In goldfish pituitary cells, Kiss1 transcript was located in somatotrophs but not in lactotrophs or gonadotrophs.

    In plain wordsIn goldfish, the gene for the body's own kisspeptin was found in growth hormone cells but not in prolactin or gonadotropin cells.

    Outcome
    MixedKiss1 transcript in pituitary cell types
    Study

    goldfishn: not reported in source

    Immuno-identified goldfish pituitary cells
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    Kiss1 transcript was also located in goldfish somatotrophs but not in lactotrophs or gonadotrophs.

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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