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Study · Measured the body's own peptide · 2009

2 results

Identification of integrins alpha6 and beta7 as c-Jun- and transformation-relevant genes in highly invasive fibrosarcoma cells.

Kielosto M, Nummela P, Järvinen K, Yin M, Hölttä E

International journal of cancer1 Sept 2009Cited by 16 (Europe PMC)

PMID19405119 (opens in a new tab)DOI10.1002/ijc.24391 (opens in a new tab)PepBankPUB-19405119
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelIn vitro (cells)Mechanism

    In AdoMetDC-transformed mouse fibroblasts, thymosin beta4 expression was upregulated.

    In plain wordsIn mouse cells turned cancer-like, the body's own thymosin beta4 gene was more active.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseThymosin beta4 expression in AdoMetDC-transformed cells
    Study

    mousen: not reported in source

    AdoMetDC-overexpressing mouse fibroblasts
    Outcome group
    Tumor growth · Cancer

    Source sentences

    Summary
    Among the small set of target genes detected were integrins alpha6 and beta7, cathepsin L and thymosin beta4, all upregulated in the AdoMetDC-transformed cells

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  2. 02LabEndogenous levelIn vitro (cells)Mechanism

    In AdoMetDC-transformed mouse fibroblasts, thymosin beta4 expression was downregulated when transformation was reversed by TAM67 or c-Jun shRNA.

    In plain wordsIn mouse cells, the body's own thymosin beta4 gene became less active when the cancer-like change was reversed.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    DecreaseThymosin beta4 expression after reversal of transformation by TAM67 or c-Jun shRNA
    Study

    mousen: not reported in source

    AdoMetDC-overexpressing mouse fibroblasts
    Outcome group
    Tumor growth · Cancer

    Source sentences

    Summary
    all upregulated in the AdoMetDC-transformed cells and downregulated upon reversal of transformation by TAM67 or c-Jun shRNA.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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