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Study · Measured the body's own peptide · 2009

2 results

Neuromuscular electrical stimulation reduces skeletal muscle protein degradation and stimulates insulin-like growth factors in an age- and current-dependent manner: a randomized, controlled clinical trial in major abdominal surgical patients.

Strasser EM, Stättner S, Karner J, Klimpfinger M, Freynhofer M, Zaller V, Graf A, Wessner B, Bachl N, Roth E, Quittan M

Annals of surgery1 May 2009Cited by 44 (Europe PMC)

PMID19387331 (opens in a new tab)DOI10.1097/sla.0b013e3181a38e71 (opens in a new tab)PepBankPUB-19387331
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelRandomized controlled trialOther

    In patients after major abdominal surgery, thigh muscle mechano growth factor mRNA level correlated positively with the applied NMES current.

    In plain wordsIn patients after abdominal surgery, the body's own MGF mRNA in thigh muscle was linked to higher electrical stimulation current.

    Peptide
    MGF / PEG-MGF
    Outcome
    IncreaseMGF mRNA correlation with applied NMES current
    Study

    n = 26

    Outcome group
    Growth hormone and IGF-1 · Musculoskeletal

    Source sentences

    Summary
    The mechano growth factor mRNA level correlated positively with the applied current and negatively with the body mass index of the patients.
    2 context sentences
    Summary · context
    This observer blind study included 26 patients after major abdominal surgery mainly due to cancer aged 60 +/- 10 years.
    Summary · context
    Starting on the first postoperative day, 1 randomly assigned thigh of each patient was treated on 4 consecutive days with NMES, whereas the other leg was used as sham-stimulated control.

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelRandomized controlled trialOther

    In patients after major abdominal surgery, thigh muscle mechano growth factor mRNA level correlated negatively with body mass index.

    In plain wordsIn patients after abdominal surgery, the body's own MGF mRNA in thigh muscle was linked to lower body mass index.

    Peptide
    MGF / PEG-MGF
    Outcome
    DecreaseMGF mRNA correlation with body mass index
    Study

    n = 26

    Outcome group
    Growth hormone and IGF-1 · Musculoskeletal

    Source sentences

    Summary
    The mechano growth factor mRNA level correlated positively with the applied current and negatively with the body mass index of the patients.
    2 context sentences
    Summary · context
    This observer blind study included 26 patients after major abdominal surgery mainly due to cancer aged 60 +/- 10 years.
    Summary · context
    Starting on the first postoperative day, 1 randomly assigned thigh of each patient was treated on 4 consecutive days with NMES, whereas the other leg was used as sham-stimulated control.

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Registered trials1

Trials this study reports on, or that list this study as a reference. Registry data from ClinicalTrials.gov.

1 trial · 1 completed · source ClinicalTrials.gov (opens in a new tab)

CompletedNot applicableNCT00635440

Randomized, Controlled Study to Investigate the Effect of Neuromuscular Electrical Stimulation (NMES) on Muscle Metabolism of Abdominal Surgical Patients

Medical University of Viennan = 26Start Dec 2005

Muscular Atrophy

Trial pageClinicalTrials.govUpdated 13 Mar 2008

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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