In mouse nasal explants, application of kisspeptin‑10 elicited a secretory response from GnRH-1 neurons.
In plain wordsIn mouse tissue samples, kisspeptin‑10 made GnRH-1 nerve cells release their hormone.
- Peptide
- Kisspeptin-10
- Outcome
- IncreaseGnRH-1 secretory response to kisspeptin-10
- Study
mousen: not reported in source
nasal explants- Outcome group
- Sex hormones and fertility · Endocrine and hormones
- Studied dose
- Dose not stated
Source sentences
The application of kisspeptin-10 revealed the ability of GnRH-1 neurons to integrate signals from natural ligands into a secretory response.
1 context sentence(design, population, supporting numbers)
In the present work, GnRH-1 release was assayed in mouse nasal explants using radioimmunology and its relationship with calcium signaling analyzed.