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Study · Animal study (in vivo) · mouse · 2009

1 result

The oral multitarget tumour growth inhibitor, ZK 304709, inhibits growth of pancreatic neuroendocrine tumours in an orthotopic mouse model.

Scholz A, Wagner K, Welzel M, Remlinger F, Wiedenmann B, Siemeister G, Rosewicz S, Detjen KM

Gut1 Oct 2008Cited by 34 (Europe PMC)

PMID18829975 (opens in a new tab)DOI10.1136/gut.2007.146415 (opens in a new tab)PepBankPUB-18829975
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In mice with orthotopic pancreatic neuroendocrine tumors, lanreotide failed to inhibit tumor growth.

    In plain wordsIn mice with pancreatic neuroendocrine tumors, lanreotide did not inhibit tumor growth.

    Peptide
    Lanreotide
    Outcome
    Direction not reportedPrimary tumor growth
    Study

    mousen: not reported in source

    Orthotopic BON pancreatic neuroendocrine tumors in NMRI(nu/nu) mice
    Outcome group
    Tumor growth · Cancer
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In contrast, treatment with lanreotide or 5-fluorouracil and streptozotocin failed to inhibit tumour gowth.
    1 context sentence
    Summary · context
    For induction of orthotopic NETs, BON cells were injected into the pancreas of NMRI(nu/nu) mice.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:36 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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