In women given a GnRH analogue before pelviscopic myomectomy, an identical myoma reduction of about 10% to 50% was seen after 3 months in 103 patients (88%) across the triptorelin and leuprorelin groups.
In plain wordsBefore fibroid surgery, triptorelin and leuprorelin groups showed the same fibroid shrinkage of about 10% to 50% after 3 months in 88% of patients.
- Outcome
- DecreaseMyoma reduction
- Study
n = 116
- Outcome group
- Sex hormones and fertility · Reproductive and sexual health
- Studied dose
- 3.75 mg · injection · 3 monthsAs given in this study (human).
Measurements
- Myoma reduction
- 10 to 50%
- about, after 3 months, both therapy groups
- Patients with myoma reduction
- 103 patients
- both therapy groups, after 3 months
- Proportion of patients with myoma reduction
- 88%
- both therapy groups, after 3 months
Source sentences
After 3 months, an identical reduction of the myomas of about 10% to 50% was observed in 103 patients (88%) in both therapy groups.
1 context sentence(design, population, supporting numbers)
One hundred sixteen patients were treated with a gonadotropin releasing hormone analogue (GnRH-a) before the pelviscopic myomaenucleation took place. In this study, 64 (55%) patients received 3,75 mg leuprorelin, and 52 (45%), patients 3.75 mg triptorelin. The monthly injections took place over a period of 3 to 6 months.