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Study · Animal study (in vivo) · cattle (holstein heifers) · 2008

2 results

Peripheral administration of kisspeptin-10 increases plasma concentrations of GH as well as LH in prepubertal Holstein heifers.

Kadokawa H, Matsui M, Hayashi K, Matsunaga N, Kawashima C, Shimizu T, Kida K, Miyamoto A

The Journal of endocrinology1 Feb 2008Cited by 60 (Europe PMC)

PMID18252956 (opens in a new tab)DOI10.1677/joe-07-0504 (opens in a new tab)PepBankPUB-18252956
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In prepubertal Holstein heifers, a single intravenous kisspeptin‑10 injection produced a peak-shaped rise in LH concentration, absent in saline controls.

    In plain wordsIn young heifers, kisspeptin‑10 caused a peak in luteinizing hormone in blood, which saline did not.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseLH response after kisspeptin-10
    Study

    cattle (Holstein heifers)n = 10

    prepubertal Holstein heifers, in vivo
    Comparator
    Saline
    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    1 mg · intravenous · single injectionAs given in this study (cattle (Holstein heifers)).

    Measurements

    Time to LH peak
    27 min
    kisspeptin-10

    Source sentences

    Summary
    Peak-shaped responses were observed for concentrations of LH and GH, and the peaks were observed at 27+/-3 and 75+/-9 min, respectively, after injection, only in heifers injected with kisspeptin-10.
    1 context sentence
    Summary · context
    Heifers received a single injection of 1 mg kisspeptin-10 (n=5) or saline (n=5) intravenously, and serial blood samples were collected at 15-min intervals to analyze the response curves of both LH and GH after injection.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In prepubertal Holstein heifers, a single intravenous kisspeptin‑10 injection produced a peak-shaped rise in GH concentration, absent in saline controls.

    In plain wordsIn young heifers, kisspeptin‑10 caused a peak in growth hormone in blood, which saline did not.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseGH response after kisspeptin-10
    Study

    cattle (Holstein heifers)n = 10

    prepubertal Holstein heifers, in vivo
    Comparator
    Saline
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    1 mg · intravenous · single injectionAs given in this study (cattle (Holstein heifers)).

    Measurements

    Time to GH peak
    75 min
    kisspeptin-10

    Source sentences

    Summary
    Peak-shaped responses were observed for concentrations of LH and GH, and the peaks were observed at 27+/-3 and 75+/-9 min, respectively, after injection, only in heifers injected with kisspeptin-10.
    1 context sentence
    Summary · context
    Heifers received a single injection of 1 mg kisspeptin-10 (n=5) or saline (n=5) intravenously, and serial blood samples were collected at 15-min intervals to analyze the response curves of both LH and GH after injection.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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