In chicken cells, a peak at m/z 4963, later identified as the body's own thymosin beta‑4, was present in monocytes/macrophages but not in granulocytes.
In plain wordsIn chicken cells, the body's own thymosin beta‑4 was found in monocytes and macrophages but not in granulocytes.
- Peptide
- Thymosin beta-4 (human)
- Outcome
- Not applicableTbeta-4 mass peak (m/z 4963) in monocytes/macrophages versus granulocytes
- Study
chickenn: not reported in source
chicken monocytes/macrophages and avian macrophage cell line HTC- Outcome group
- Immune response · Immune and inflammation
Source sentences
The mass spectra showed a prominent peak at m/z 4963 in monocytes/macrophages but not in the granulocytes. Subsequent purification and characterization of the m/z 4963 peptide from an avian macrophage cell line HTC, revealed it to be thymosin beta-4 (Tbeta-4), an actin-modulating peptide.
1 context sentence(design, population, supporting numbers)
The aim of the study was to determine chicken monocyte- and granulocyte-associated peptides and proteins using "whole cell" matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry (MALDI-TOF MS) and to characterize the peptides based on their abundance.
This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.