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Study · Not a test of the peptide alone · 2007

2 results

Mapping the specific cytoprotective interaction of humanin with the pro-apoptotic protein bid.

Choi J, Zhai D, Zhou X, Satterthwait A, Reed JC, Marassi FM

Chemical biology & drug design10 Oct 2007Cited by 18 (Europe PMC)

PMID17927731 (opens in a new tab)PMCIDPMC2917600 (opens in a new tab)DOI10.1111/j.1747-0285.2007.00576.x (opens in a new tab)PepBankPUB-17927731
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Humanin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Humanin.

  1. 01LabNot a test of Humanin aloneIn vitro (cell-free)Mechanism

    In NMR chemical shift mapping, Humanin-derived peptides interacted specifically with the pro-apoptotic protein Bid.

    In plain wordsIn lab tests, peptides derived from humanin bound specifically to the cell-death protein Bid.

    Peptide
    Humanin
    Outcome
    Not applicableBinding of Humanin-derived peptides to Bid
    Study

    n: not reported in source

    NMR chemical shift mapping
    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    we demonstrate that the interaction between Humanin-derived peptides and Bid is specific
    1 context sentence
    Title · context
    Mapping the specific cytoprotective interaction of humanin with the pro-apoptotic protein bid.

    In this study, Humanin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Humanin.

  2. 02LabNot a test of Humanin aloneIn vitro (cell-free)Mechanism

    NMR mapping placed the binding site of Humanin-derived peptides on the surface of Bid, in a region that includes residues of the conserved helical BH3 domain.

    In plain wordsIn lab tests, humanin-derived peptides bound a surface region of the Bid protein that includes part of its BH3 domain.

    Peptide
    Humanin
    Outcome
    Not applicableBid binding site location for Humanin-derived peptides
    Study

    n: not reported in source

    NMR chemical shift mapping
    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    and we localize the binding site to a region on the surface of Bid, which includes residues from the conserved helical BH3 domain of the protein.

    In this study, Humanin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Humanin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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