Ovulation induced by mucosa vaginal absorption of buserelin and triptorelin in rabbit.

Viudes-de-Castro MP, Lavara R, Marco-Jiménez F, Cortell C, Vicente JS

Theriogenology12 Sept 2007Cited by 22 (Europe PMC)

PMID17854884DOI10.1016/j.theriogenology.2007.08.004PepBankPUB-17854884

Publisher page PubMedAsk about this study

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study8

8 results from studies that gave the peptide. No result from this study comes from people.

01AnimalAnimal study (in vivo)Efficacy outcome
In rabbit does, ovulation rate with triptorelin-supplemented extender was similar across experimental groups.
In plain wordsIn rabbits, ovulation rate with triptorelin-supplemented extender was similar to the other experimental groups.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
No significant changeOvulation rate with lower triptorelin dose
Study
rabbitn: not reported in source
Receptive does undergoing artificial insemination
Comparator
Other experimental groups
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
2 microg per female · vaginal mucosal absorption through supplemented semen extenderAs given in this study (rabbit).
Source sentences
Summary
Ovulation rate was similar in all groups (11.4-12.5).
1 context sentence(design, population, supporting numbers)
Summary · context
T2 (2 microg per female triptorelin supplemented extender) and T5 (5 microg per female triptorelin supplemented extender).
Report a problemFND-1785488401
02AnimalAnimal study (in vivo)Efficacy outcome
In rabbit does, ovulation rate with triptorelin-supplemented extender was similar across experimental groups.
In plain wordsIn rabbits, ovulation rate with triptorelin-supplemented extender was similar to the other experimental groups.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
No significant changeOvulation rate with higher triptorelin dose
Study
rabbitn: not reported in source
Receptive does undergoing artificial insemination
Comparator
Other experimental groups
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
5 microg per female · vaginal mucosal absorption through supplemented semen extenderAs given in this study (rabbit).
Source sentences
Summary
Ovulation rate was similar in all groups (11.4-12.5).
1 context sentence(design, population, supporting numbers)
Summary · context
T2 (2 microg per female triptorelin supplemented extender) and T5 (5 microg per female triptorelin supplemented extender).
Report a problemFND-1785488402
03AnimalAnimal study (in vivo)Efficacy outcome
In rabbit does, triptorelin-supplemented extender did not reach the ovulation induction response of intramuscular buserelin controls.
In plain wordsIn rabbits, triptorelin-supplemented extender did not reach the ovulation induction response of injected buserelin controls.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
DecreaseOvulation induction response with lower triptorelin dose
Study
rabbitn: not reported in source
Receptive does undergoing artificial insemination
Comparator
1 microg intramuscular buserelin
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
2 microg per female · vaginal mucosal absorption through supplemented semen extenderAs given in this study (rabbit).
Source sentences
Summary
Only B5 females reached similar ovulation induction response than PC group.
2 context sentences(design, population, supporting numbers)
Summary · context
The efficiency of ovulation induction was very low (32.5%) in NC group and showed the higher results in PC females (97.8%).
Summary · context
T2 (2 microg per female triptorelin supplemented extender) and T5 (5 microg per female triptorelin supplemented extender).
Report a problemFND-1785488403
04AnimalAnimal study (in vivo)Efficacy outcome
In rabbit does, triptorelin-supplemented extender did not reach the ovulation induction response of intramuscular buserelin controls.
In plain wordsIn rabbits, triptorelin-supplemented extender did not reach the ovulation induction response of injected buserelin controls.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
DecreaseOvulation induction response with higher triptorelin dose
Study
rabbitn: not reported in source
Receptive does undergoing artificial insemination
Comparator
1 microg intramuscular buserelin
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
5 microg per female · vaginal mucosal absorption through supplemented semen extenderAs given in this study (rabbit).
Source sentences
Summary
Only B5 females reached similar ovulation induction response than PC group.
2 context sentences(design, population, supporting numbers)
Summary · context
The efficiency of ovulation induction was very low (32.5%) in NC group and showed the higher results in PC females (97.8%).
Summary · context
T2 (2 microg per female triptorelin supplemented extender) and T5 (5 microg per female triptorelin supplemented extender).
Report a problemFND-1785488404
05AnimalAnimal study (in vivo)Efficacy outcome
In rabbit does, fertility rate with triptorelin-supplemented extender was similar to intramuscular buserelin and buserelin-supplemented extender.
In plain wordsIn rabbits, fertility with triptorelin-supplemented extender was similar to injected buserelin and buserelin-supplemented extender.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
No significant changeFertility rate
Study
rabbitn: not reported in source
Receptive does undergoing artificial insemination
Comparator
Intramuscular buserelin and buserelin-supplemented extender
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
5 microg per female · vaginal mucosal absorption through supplemented semen extenderAs given in this study (rabbit).
Source sentences
Summary
Fertility and prolificacy parameters were similar among the groups (77.8% fertility rate, 73.9% kindling rate, 9.4 live born and 9.9 total born).
1 context sentence(design, population, supporting numbers)
Summary · context
to compare fertility and prolificacy parameters from the conventional insemination technique (control group, females treated with 1 microg per female of buserelin intramuscularly) versus a supplementation with buserelin or triptorelin (5 microg per female) in semen extender (B5 and T5 groups, respectively).
Report a problemFND-1785488405
06AnimalAnimal study (in vivo)Efficacy outcome
In rabbit does, kindling rate with triptorelin-supplemented extender was similar to intramuscular buserelin and buserelin-supplemented extender.
In plain wordsIn rabbits, birth rate with triptorelin-supplemented extender was similar to injected buserelin and buserelin-supplemented extender.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
No significant changeKindling rate
Study
rabbitn: not reported in source
Receptive does undergoing artificial insemination
Comparator
Intramuscular buserelin and buserelin-supplemented extender
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
5 microg per female · vaginal mucosal absorption through supplemented semen extenderAs given in this study (rabbit).
Source sentences
Summary
Fertility and prolificacy parameters were similar among the groups (77.8% fertility rate, 73.9% kindling rate, 9.4 live born and 9.9 total born).
1 context sentence(design, population, supporting numbers)
Summary · context
to compare fertility and prolificacy parameters from the conventional insemination technique (control group, females treated with 1 microg per female of buserelin intramuscularly) versus a supplementation with buserelin or triptorelin (5 microg per female) in semen extender (B5 and T5 groups, respectively).
Report a problemFND-1785488406
07AnimalAnimal study (in vivo)Efficacy outcome
In rabbit does, live-born offspring counts with triptorelin-supplemented extender were similar to intramuscular buserelin and buserelin-supplemented extender.
In plain wordsIn rabbits, live-born offspring counts with triptorelin-supplemented extender were similar to injected buserelin and buserelin-supplemented extender.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
No significant changeLive-born offspring
Study
rabbitn: not reported in source
Receptive does undergoing artificial insemination
Comparator
Intramuscular buserelin and buserelin-supplemented extender
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
5 microg per female · vaginal mucosal absorption through supplemented semen extenderAs given in this study (rabbit).
Source sentences
Summary
Fertility and prolificacy parameters were similar among the groups (77.8% fertility rate, 73.9% kindling rate, 9.4 live born and 9.9 total born).
1 context sentence(design, population, supporting numbers)
Summary · context
to compare fertility and prolificacy parameters from the conventional insemination technique (control group, females treated with 1 microg per female of buserelin intramuscularly) versus a supplementation with buserelin or triptorelin (5 microg per female) in semen extender (B5 and T5 groups, respectively).
Report a problemFND-1785488407
08AnimalAnimal study (in vivo)Efficacy outcome
In rabbit does, total offspring counts with triptorelin-supplemented extender were similar to intramuscular buserelin and buserelin-supplemented extender.
In plain wordsIn rabbits, total offspring counts with triptorelin-supplemented extender were similar to injected buserelin and buserelin-supplemented extender.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
No significant changeTotal offspring born
Study
rabbitn: not reported in source
Receptive does undergoing artificial insemination
Comparator
Intramuscular buserelin and buserelin-supplemented extender
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
5 microg per female · vaginal mucosal absorption through supplemented semen extenderAs given in this study (rabbit).
Source sentences
Summary
Fertility and prolificacy parameters were similar among the groups (77.8% fertility rate, 73.9% kindling rate, 9.4 live born and 9.9 total born).
1 context sentence(design, population, supporting numbers)
Summary · context
to compare fertility and prolificacy parameters from the conventional insemination technique (control group, females treated with 1 microg per female of buserelin intramuscularly) versus a supplementation with buserelin or triptorelin (5 microg per female) in semen extender (B5 and T5 groups, respectively).
Report a problemFND-1785488408

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
22 Oct 2026, 02:26 UTC
Study results updated
Version 1
21 Oct 2026, 18:59 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

MeSH terms

PepBank is a research reference. Talk to a doctor before you use any peptide.