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Study · In vitro (cells) · bovine and porcine · 2008

3 results

Direct kisspeptin-10 stimulation on luteinizing hormone secretion from bovine and porcine anterior pituitary cells.

Suzuki S, Kadokawa H, Hashizume T

Animal reproduction science31 May 2007Cited by 84 (Europe PMC)

PMID17604578 (opens in a new tab)DOI10.1016/j.anireprosci.2007.05.016 (opens in a new tab)PepBankPUB-17604578
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Activity measurement

    In bovine anterior pituitary cells, kisspeptin‑10 at 1000 nM and 10,000 nM, but not at lower concentrations, increased LH secretion.

    In plain wordsIn bovine pituitary cells, kisspeptin‑10 raised LH release at high concentrations but not at lower ones.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseLH secretion from bovine anterior pituitary cells
    Study

    bovinen: not reported in source

    anterior pituitary cells
    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    1000 nM and 10,000 nM · in vitro incubation · 2 hAs given in this study (bovine).

    Source sentences

    Summary
    The 1000 nM and 10,000 nM, but not lower concentrations, of kisspeptin-10 significantly stimulated LH secretion from the bovine AP cells (P<0.05).
    1 context sentence
    Summary · context
    The AP cells were prepared from 1-month-old intact male calves, 8-month-old castrated male calves, or 6-month-old barrows, and then the cells were incubated for 2h with the peptides.
  2. 02LabIn vitro (cells)Activity measurement

    In porcine anterior pituitary cells, kisspeptin‑10 at 100 nM and 1000 nM, but not at lower concentrations, increased LH secretion.

    In plain wordsIn pig pituitary cells, kisspeptin‑10 raised LH release at 100 and 1000 nM but not at lower concentrations.

    Peptide
    Kisspeptin-10
    Outcome
    IncreaseLH secretion from porcine anterior pituitary cells
    Study

    porcinen: not reported in source

    anterior pituitary cells
    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    100 nM and 1000 nM · in vitro incubation · 2 hAs given in this study (porcine).

    Source sentences

    Summary
    The 100 nM and 1000 nM, but not lower concentrations, of kisspeptin-10 significantly stimulated LH secretion from porcine AP cells (P<0.05).
    1 context sentence
    Summary · context
    The AP cells were prepared from 1-month-old intact male calves, 8-month-old castrated male calves, or 6-month-old barrows, and then the cells were incubated for 2h with the peptides.
  3. 03LabIn vitro (cells)Activity measurement

    In bovine and porcine anterior pituitary cells, kisspeptin‑10 stimulated LH secretion directly but more weakly than 10 nM GnRH.

    In plain wordsIn bovine and pig pituitary cells, kisspeptin‑10 raised LH release, but less strongly than GnRH.

    Peptide
    Kisspeptin-10
    Outcome
    DecreaseLH secretion relative to GnRH
    Study

    bovine and porcinen: not reported in source

    anterior pituitary cells
    Comparator
    GnRH 10 nM
    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    Dose not stated · in vitro incubation · 2 hAs given in this study (bovine and porcine).

    Source sentences

    Summary
    As 10nM of GnRH strongly stimulated LH secretion from all AP cells tested in this study, the present results suggest that kisspeptin-10 has a direct, but weak, stimulating effect on LH secretion in bovine and porcine AP cells.
    1 context sentence
    Summary · context
    The AP cells were prepared from 1-month-old intact male calves, 8-month-old castrated male calves, or 6-month-old barrows, and then the cells were incubated for 2h with the peptides.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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