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Study · Observational study · n = 25 · 2007

1 result

Serum sex hormone-binding globulin levels in healthy children and girls with precocious puberty before and during gonadotropin-releasing hormone agonist treatment.

Sørensen K, Andersson AM, Skakkebaek NE, Juul A

The Journal of clinical endocrinology and metabolism22 May 2007Cited by 48 (Europe PMC)

PMID17519314 (opens in a new tab)DOI10.1210/jc.2007-0231 (opens in a new tab)PepBankPUB-17519314
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. 1 result from people.

  1. 01HumanObservational studyEfficacy outcome

    In girls with precocious puberty, SHBG declined further during triptorelin treatment compared with pretreatment levels.

    In plain wordsIn girls with precocious puberty, SHBG fell during triptorelin treatment compared with pretreatment levels.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    DecreaseSHBG during treatment
    Study

    n = 25

    Comparator
    Pretreatment SHBG level
    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    Dose not stated · 2 yearsAs given in this study (human).

    Measurements

    SHBG SD score
    −1.29 SD score
    pretreatment
    SHBG SD score
    −2.75 SD score
    during treatment

    Source sentences

    Summary
    Girls with CPP had significantly lower pretreatment SHBG levels compared with age-matched controls [SHBG sd score, -1.29 (-4.48; 0.01)], which declined even further during GnRHa treatment [-2.75 (-5.9; 0.53); P < 0.001].
    2 context sentences
    Summary · context
    We conducted a cross-sectional study on healthy subjects and a 2-yr longitudinal study in girls with CPP.
    Summary · context
    Girls with CPP were treated with the long-acting GnRHa triptorelin.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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