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Study · Animal study (in vivo) · cba mice · 2006

4 results

[Biologically active thymic factors and melatonin-producing pineal function in mice in aging].

Labunets' IF

Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994)1 Jan 2006

PMID17333624 (opens in a new tab)PepBankPUB-17333624
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In adult mice, a single thymaline injection significantly increased serum melatonin after 3 h.

    In plain wordsIn mice, a single thymaline injection increased blood melatonin after 3 h in adult animals.

    Peptide
    Thymalin
    Outcome
    IncreaseSerum melatonin
    Study

    CBA micen: not reported in source

    Adult mice
    Outcome group
    Sleep · Endocrine and hormones
    Studied dose
    Dose not stated · injectionAs given in this study (CBA mice).

    Source sentences

    Summary
    It was shown that in serum of the adult mice (3-4 m) melatonin level increased significantly in 3 h after one injection of thymic preparation "thymaline".
    1 context sentence
    Summary · context
    The aging peculiarities of thymic factors influence on pineal gland function in CBA mice were investigated.
  2. 02AnimalAnimal study (in vivo)Mechanism

    In adult mice, thymaline activation depended on season and was linked to increased FTS levels.

    In plain wordsIn mice, thymaline activation depended on season and was linked to increased FTS levels in adult animals.

    Peptide
    Thymalin
    Outcome
    IncreaseFTS level
    Study

    CBA micen: not reported in source

    Adult mice
    Outcome group
    Immune response · Endocrine and hormones
    Studied dose
    Dose not stated · injectionAs given in this study (CBA mice).

    Source sentences

    Summary
    The activating influence ofthymaline depended on season and linked with increased level of thymic serum factor (FTS).
    1 context sentence
    Summary · context
    The aging peculiarities of thymic factors influence on pineal gland function in CBA mice were investigated.
  3. 03AnimalAnimal study (in vivo)Mechanism

    In old mice, thymaline administration produced no pineal seasonal response.

    In plain wordsIn mice, thymaline produced no seasonal pineal response in old animals.

    Peptide
    Thymalin
    Outcome
    No significant changePineal seasonal response
    Study

    CBA micen: not reported in source

    Old mice
    Outcome group
    Sleep · Endocrine and hormones
    Studied dose
    Dose not stated · injectionAs given in this study (CBA mice).

    Source sentences

    Summary
    There was no activating influence of thymic factors on pineal function of old mice (23-24 mo) in vivo and in vitro as well as the pineal seasonal reaction on the administration of thymaline.
    1 context sentence
    Summary · context
    The aging peculiarities of thymic factors influence on pineal gland function in CBA mice were investigated.
  4. 04AnimalAnimal study (in vivo)Mechanism

    In old mice, thymic factors including thymaline showed no activating influence on pineal function in vivo.

    In plain wordsIn old mice, thymic factors including thymaline did not activate pineal function in the living animals.

    Peptide
    Thymalin
    Outcome
    No significant changePineal activation by thymic factors
    Study

    CBA micen: not reported in source

    Old mice
    Outcome group
    Sleep · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    There was no activating influence of thymic factors on pineal function of old mice (23-24 mo) in vivo and in vitro as well as the pineal seasonal reaction on the administration of thymaline.
    2 context sentences
    Summary · context
    It was shown that in serum of the adult mice (3-4 m) melatonin level increased significantly in 3 h after one injection of thymic preparation "thymaline".
    Summary · context
    The aging peculiarities of thymic factors influence on pineal gland function in CBA mice were investigated.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    21 Oct 2026, 12:50 UTC

    Study data updated · source update from Europe PMC

  2. Version 2

    14 Oct 2026, 05:02 UTC

    Study results updated

  3. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

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