In tuberculosis patients with neurotoxic reactions, cortexin permitted 90.9% to continue isoniazid, whereas 42.2% of controls resumed isoniazid.
In plain wordsIn tuberculosis patients with neurotoxic reactions, 90.9% continued isoniazid with cortexin, whereas 42.2% resumed it with control treatment.
- Outcome
- IncreaseContinuation or resumption of isoniazid
- Study
n = 41
- Comparator
- gamma or vitamins B with glutaminic acid
- Outcome group
- Adverse events · Nervous system and cognition
- Studied dose
- Dose not stated
Measurements
- Isoniazid continuation
- 90.9%
- cortexin
- Isoniazid resumption
- 42.2%
- control treatment
Source sentences
Cortexin used in the therapy of neurotoxic reactions produced a beneficial effect and permitted 90.9% of the patients to continue to use isoniazid while 42.2% of the controls resumed using isoniazid.
1 context sentence(design, population, supporting numbers)
Therapy for neurotoxic reactions used cortexin in the study group (n = 22) and gamma or vitamins B in combination with glutaminic acid in the control group (n = 19).