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Study · Not a test of the peptide alone · 2006

3 results

Assessing adrenal function in primary care settings with a single sample subcutaneous glucagon test.

Kappy MS, Drake A, Gao D, Ratliff R

The Journal of pediatrics1 Nov 2006Cited by 11 (Europe PMC)

PMID17095343 (opens in a new tab)DOI10.1016/j.jpeds.2006.07.033 (opens in a new tab)PepBankPUB-17095343
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, Glucagon was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Glucagon.

  1. 01HumanNot a test of Glucagon aloneNon-randomized trialActivity measurement

    In healthy children, mean peak cortisol after subcutaneous glucagon was 22.4 +/- 0.6 microg/dL (SEM).

    In plain wordsIn healthy children, mean peak cortisol after a subcutaneous glucagon test was 22.4 microg/dL.

    Peptide
    Glucagon
    Outcome
    Not applicablePeak serum cortisol
    Study

    n = 215

    Outcome group
    Stress hormones · Endocrine and hormones

    Measurements

    Mean peak serum cortisol
    22.4 microg/dL
    after subcutaneous glucagon, 215 healthy children (± 0.6 SEM)

    Source sentences

    Summary
    Mean peak serum cortisol concentrations were 22.4 +/- 0.6 microg/dL (SEM) after subcutaneous glucagon and 20.0 +/- 0.6 microg/dL after intravenous ACTH.
    2 context sentences
    Summary · context
    Subcutaneous glucagon was used to assess the hypothalamo-pituitary-adrenal gland (HPA) axis in 215 healthy children.
    Summary · context
    Concordance of this test with the low-dose intravenous ACTH test was established for 42 children.

    In this study, Glucagon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Glucagon.

  2. 02HumanNot a test of Glucagon aloneNon-randomized trialActivity measurement

    In healthy children, glucagon and ACTH tests had 90.5% concordance.

    In plain wordsIn healthy children, the glucagon test and the low-dose ACTH test had 90.5% concordance.

    Peptide
    Glucagon
    Outcome
    Not applicableConcordance with ACTH test
    Study

    n = 42

    Comparator
    low-dose intravenous ACTH test
    Outcome group
    Stress hormones · Endocrine and hormones

    Measurements

    Concordance with low-dose intravenous ACTH test
    90.5%
    glucagon test versus ACTH test, 42 children

    Source sentences

    Summary
    Concordance between the glucagon and ACTH tests was 90.5%.
    2 context sentences
    Summary · context
    Subcutaneous glucagon was used to assess the hypothalamo-pituitary-adrenal gland (HPA) axis in 215 healthy children.
    Summary · context
    Concordance of this test with the low-dose intravenous ACTH test was established for 42 children.

    In this study, Glucagon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Glucagon.

  3. 03HumanNot a test of Glucagon aloneNon-randomized trialActivity measurement

    In healthy children, the glucagon test had 95% specificity at peak cortisol of 9.5 microg/dL.

    In plain wordsIn healthy children, the glucagon test had 95% specificity at the reported cortisol threshold.

    Peptide
    Glucagon
    Outcome
    Not applicableCortisol test specificity
    Study

    n: not reported in source

    Outcome group
    Stress hormones · Endocrine and hormones

    Measurements

    Specificity
    95%
    glucagon test
    Peak cortisol cutoff for glucagon test
    9.5 microg/dL
    at 95% specificity

    Source sentences

    Summary
    Specificity of 95% was found at peak cortisol concentrations of 9.5 and 12.5 microg/dL for the glucagon and ACTH tests, respectively.
    2 context sentences
    Summary · context
    Subcutaneous glucagon was used to assess the hypothalamo-pituitary-adrenal gland (HPA) axis in 215 healthy children.
    Summary · context
    Concordance of this test with the low-dose intravenous ACTH test was established for 42 children.

    In this study, Glucagon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Glucagon.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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