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Study · Not a test of the peptide alone · 2007

2 results

Neither intravenous nor intracerebroventricular administration of obestatin affects the secretion of GH, PRL, TSH and ACTH in rats.

Yamamoto D, Ikeshita N, Daito R, Herningtyas EH, Toda K, Takahashi K, Iida K, Takahashi Y, Kaji H, Chihara K, Okimura Y

Regulatory peptides19 Oct 2006Cited by 58 (Europe PMC)

PMID17055593 (opens in a new tab)DOI10.1016/j.regpep.2006.09.001 (opens in a new tab)PepBankPUB-17055593
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, GHRP-2 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking GHRP-2.

  1. 01AnimalNot a test of GHRP-2 aloneAnimal study (in vivo)Efficacy outcome

    In anesthetized male rats, intravenous GHRP‑2 resulted in a marked plasma GH elevation.

    In plain wordsIn rats, GHRP‑2 given into a vein caused a marked rise in blood growth hormone.

    Peptide
    GHRP-2
    Outcome
    IncreasePlasma GH after intravenous GHRP-2
    Study

    ratn: not reported in source

    anesthetized male rats
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    Intravenous administration of GHRH or GHRP-2, a ghrelin receptor ligand, resulted in a marked plasma GH elevation.
    1 context sentence
    Summary · context
    To examine the effect of obestatin, a recently identified peptide derived from preproghrelin, on pituitary hormone secretion, obestatin was administered in anesthetized male rats.

    In this study, GHRP-2 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-2.

  2. 02AnimalNot a test of GHRP-2 aloneAnimal study (in vivo)Efficacy outcome

    In anesthetized male rats, obestatin did not change the GHRP‑2-induced rise in plasma GH.

    In plain wordsIn rats, obestatin did not change the growth hormone rise that GHRP‑2 caused.

    Peptide
    GHRP-2
    Outcome
    No significant changeObestatin effect on GHRP-2-induced GH rise
    Study

    ratn: not reported in source

    anesthetized male rats
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    However obestatin did not show any effect on GHRH- or GHRP-2-induced GH rise.
    1 context sentence
    Summary · context
    To examine the effect of obestatin, a recently identified peptide derived from preproghrelin, on pituitary hormone secretion, obestatin was administered in anesthetized male rats.

    In this study, GHRP-2 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-2.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    27 Oct 2026, 16:35 UTC

    Study data updated · source update from Europe PMC

  2. Version 2

    13 Oct 2026, 21:44 UTC

    Study results updated

  3. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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