In mice with UV-induced fibrosarcoma, the body's own thymosin beta‑4 was identified among secreted proteins of tumor masses at the progressive stage.
In plain wordsIn mice with tumors, the body's own thymosin beta‑4 was found in fluid from growing tumors.
- Peptide
- Thymosin beta-4 (human)
- Outcome
- Not applicableThymosin beta 4 in progressive-stage tumor secretome
- Study
mousen: not reported in source
UV-2240 fibrosarcoma tumor masses- Outcome group
- Endogenous peptide levels · Cancer
Source sentences
Five secreted proteins (cyclophilin-A, S100A4, profilin-1, thymosin beta 4 and 10), previously associated with tumor progression, were identified from tumor masses at the progressive stage.
1 context sentence(design, population, supporting numbers)
A UV-induced skin fibrosarcoma cell line (UV-2240) was subcutaneously injected into C3H/NeH mice, resulting in tumor masses that initially progressed, then regressed and eventually eradicated.
This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.