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Study · In vitro (cells) · 2006

2 results

Zyxin is upregulated in the nucleus by thymosin beta4 in SiHa cells.

Moon HS, Even-Ram S, Kleinman HK, Cha HJ

Experimental cell research2 Aug 2006Cited by 23 (Europe PMC)

PMID16956606 (opens in a new tab)DOI10.1016/j.yexcr.2006.07.021 (opens in a new tab)PepBankPUB-16956606
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Mechanism

    In SiHa cells, zyxin and thymosin beta4 both showed increased localization in the nucleus.

    In plain wordsIn lab-grown SiHa cells, both zyxin and thymosin beta4 were found more often in the cell nucleus.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseNuclear localization of zyxin and thymosin beta4
    Study

    n: not reported in source

    SiHa cells
    Outcome group
    Receptor activity and mechanism · Cancer
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Both zyxin and thymosin beta4 show increased localization in the nucleus.

Studies that did not test the peptide alone1

In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin beta-4 (human).

  1. 02LabNot a test of Thymosin beta-4 (human) aloneIn vitro (cells)Mechanism

    In SiHa cells, exogenous or overexpressed thymosin beta4 increased zyxin expression.

    In plain wordsIn SiHa cells, adding Tβ4 or raising Tβ4 gene activity increased zyxin levels.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseZyxin expression in SiHa cells
    Study

    n: not reported in source

    SiHa cells
    Outcome group
    Receptor activity and mechanism · Cancer

    Source sentences

    Summary
    We searched for genes upregulated by thymosin beta4 and identified zyxin as increased in SiHa cells in the presence of exogenously added thymosin beta4 and when thymosin beta4 is overexpressed using adenoviral vectors.

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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