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Study · Measured the body's own peptide · 2007

4 results

Occurrence of thymosin beta4 in human breast cancer cells and in other cell types of the tumor microenvironment.

Larsson LI, Holck S

Human pathology1 Sept 2006Cited by 28 (Europe PMC)

PMID16949646 (opens in a new tab)DOI10.1016/j.humpath.2006.06.025 (opens in a new tab)PepBankPUB-16949646
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured4

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyMechanism

    In human breast tumors, cancer cells showed low or intermediate thymosin beta4 reactivity, while leukocytes and macrophages showed intense reactivity.

    In plain wordsIn human breast tumors, the body's own thymosin beta4 was low or intermediate in cancer cells and intense in immune cells.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableThymosin beta4 staining in cancer cells versus leukocytes and macrophages
    Study

    n: not reported in source

    Outcome group
    Synthesis and manufacturing · Cancer

    Source sentences

    Summary
    In most tumors examined, cancer cells showed low or intermediate reactivity for thymosin beta4, whereas leukocytes and macrophages showed intense reactivity.
    1 context sentence
    Summary · context
    We now demonstrate that there is a considerable heterogeneity in the cellular distribution of thymosin beta4 in breast cancer.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyMechanism

    In human breast tumors, endothelial cells showed variable thymosin beta4 reactivity, and myofibroblasts were negative.

    In plain wordsIn human breast tumors, the body's own thymosin beta4 varied in blood vessel lining cells and was absent in myofibroblasts.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableThymosin beta4 staining in endothelial cells and myofibroblasts
    Study

    n: not reported in source

    Outcome group
    Synthesis and manufacturing · Cancer

    Source sentences

    Summary
    In addition, endothelial cells showed variable reactivity to thymosin beta4, whereas myofibroblasts were negative.
    1 context sentence
    Summary · context
    We now demonstrate that there is a considerable heterogeneity in the cellular distribution of thymosin beta4 in breast cancer.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelObservational studyMechanism

    In human breast cancer, tumor cell thymosin beta4 staining intensity did not correlate with histological grade.

    In plain wordsIn human breast cancer, the body's own thymosin beta4 staining in tumor cells was not linked to tumor grade.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    No significant changeTumor cell thymosin beta4 staining and histological grade
    Study

    n: not reported in source

    Outcome group
    Synthesis and manufacturing · Cancer

    Source sentences

    Summary
    There was no correlation between the intensity of tumor cell staining and histological grade
    1 context sentence
    Summary · context
    We now demonstrate that there is a considerable heterogeneity in the cellular distribution of thymosin beta4 in breast cancer.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  4. 04HumanEndogenous levelObservational studyMechanism

    In human breast cancer, endothelial cell thymosin beta4 staining showed a tendency toward correlation with histological grade.

    In plain wordsIn human breast cancer, the body's own thymosin beta4 in blood vessel lining cells tended to be linked to tumor grade.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableEndothelial cell thymosin beta4 staining and histological grade
    Study

    n: not reported in source

    Outcome group
    Synthesis and manufacturing · Cancer

    Source sentences

    Summary
    whereas there was a tendency toward a correlation between endothelial cell staining and grade.
    1 context sentence
    Summary · context
    We now demonstrate that there is a considerable heterogeneity in the cellular distribution of thymosin beta4 in breast cancer.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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