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Study · Measured the body's own peptide · 2006

1 result

The role of nicotinamide adenine dinucleotide phosphate oxidase-derived reactive oxygen species in the acquisition of metastatic ability of tumor cells.

Okada F, Kobayashi M, Tanaka H, Kobayashi T, Tazawa H, Iuchi Y, Onuma K, Hosokawa M, Dinauer MC, Hunt NH

The American journal of pathology1 Jul 2006Cited by 37 (Europe PMC)

PMID16816381 (opens in a new tab)PMCIDPMC1698756 (opens in a new tab)DOI10.2353/ajpath.2006.060073 (opens in a new tab)PepBankPUB-16816381
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In mice, tumors from wild-type mice showed Tbeta4 gene expression and cell motility/invasion, but tumors from gp91(phox-/-) mice did not.

    In plain wordsIn mice, the body's own Tbeta4 gene was active in tumors from normal mice but not from mice lacking gp91(phox).

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseTbeta4 gene expression in tumors
    Study

    mousen: not reported in source

    gp91(phox-/-) and C57BL/6J wild-type mice with tumors
    Comparator
    gp91(phox-/-) mice
    Outcome group
    Tumor growth · Cancer

    Source sentences

    Summary
    Thymosin beta4 gene expression and cell motility/invasion were seen in the tumors from WT mice but not in those from gp91(phox-/-) mice.
    1 context sentence
    Summary · context
    We examined the role of phagocyte-derived oxygen radicals in tumor cell acquisition of metastatic phenotype by comparing gp91(phox-/-) mice and C57BL/6J wild-type (WT) mice.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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