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Study · Measured the body's own peptide · 2006

4 results

Kisspeptin immunoreactive cells of the ovine preoptic area and arcuate nucleus co-express estrogen receptor alpha.

Franceschini I, Lomet D, Cateau M, Delsol G, Tillet Y, Caraty A

Neuroscience letters18 Apr 2006Cited by 369 (Europe PMC)

PMID16621281 (opens in a new tab)DOI10.1016/j.neulet.2006.03.039 (opens in a new tab)PepBankPUB-16621281
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured4

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelEx vivo tissueOther

    In the ovine hypothalamus, kp10-immunoreactive cells were most numerous in the caudal arcuate nucleus, dorsomedial nucleus and medial preoptic area.

    In plain wordsIn sheep brain tissue, the body's own kisspeptin cells were most common in three hypothalamic areas.

    Peptide
    Kisspeptin-10
    Outcome
    Not applicableDistribution of kp10-immunoreactive cells in ovine hypothalamus
    Study

    sheepn: not reported in source

    ovine hypothalamic tissue
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    Kp10-ir cells were predominant in the caudal arcuate nucleus, the dorsomedial nucleus and the medial preoptic area.
    1 context sentence
    Summary · context
    We have raised specific rabbit antisera against a highly conserved 10 amino acid-amidated peptide (kp10) common to all kisspeptin isoforms isolated so far and mapped the distribution of kp10-immunoreactive (ir) cells in the ovine hypothalamus.

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

  2. 02LabEndogenous levelEx vivo tissueOther

    In the ovine hypothalamus, many kp10-immunoreactive fibers lay in the preoptic area and the median eminence.

    In plain wordsIn sheep brain tissue, the body's own kisspeptin fibers reached the area where GnRH neurons sit and the median eminence.

    Peptide
    Kisspeptin-10
    Outcome
    Not applicableDistribution of kp10-immunoreactive fibers
    Study

    sheepn: not reported in source

    ovine hypothalamic tissue
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    Numerous varicose kp10-ir fibers were found in the preoptic area where GnRH neurons reside and in the median eminence, seemingly projecting around small capillaries in its external zone.
    1 context sentence
    Summary · context
    We have raised specific rabbit antisera against a highly conserved 10 amino acid-amidated peptide (kp10) common to all kisspeptin isoforms isolated so far and mapped the distribution of kp10-immunoreactive (ir) cells in the ovine hypothalamus.

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

  3. 03LabEndogenous levelEx vivo tissueOther

    In the ovine caudal arcuate nucleus, nearly all kp10-immunoreactive cells also carried estradiol receptor alpha.

    In plain wordsIn sheep brain tissue, almost all of the body's own kisspeptin cells in the arcuate nucleus also carried the estrogen receptor.

    Peptide
    Kisspeptin-10
    Outcome
    Not applicableEstrogen receptor alpha co-expression in arcuate nucleus kp10 cells
    Study

    sheepn: not reported in source

    ovine hypothalamic tissue
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    Within the caudal arcuate nucleus, nearly all kp10-ir cells showed an intense estradiol receptor alpha immunofluorescent signal compared with approximately half of kp10-ir cells in the preoptic area.
    1 context sentence
    Summary · context
    We have raised specific rabbit antisera against a highly conserved 10 amino acid-amidated peptide (kp10) common to all kisspeptin isoforms isolated so far and mapped the distribution of kp10-immunoreactive (ir) cells in the ovine hypothalamus.

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

  4. 04LabEndogenous levelEx vivo tissueOther

    In the ovine preoptic area, about half of kp10-immunoreactive cells carried estradiol receptor alpha.

    In plain wordsIn sheep brain tissue, about half of the body's own kisspeptin cells in the preoptic area also carried the estrogen receptor.

    Peptide
    Kisspeptin-10
    Outcome
    Not applicableEstrogen receptor alpha co-expression in preoptic area kp10 cells
    Study

    sheepn: not reported in source

    ovine hypothalamic tissue
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    Within the caudal arcuate nucleus, nearly all kp10-ir cells showed an intense estradiol receptor alpha immunofluorescent signal compared with approximately half of kp10-ir cells in the preoptic area.
    1 context sentence
    Summary · context
    We have raised specific rabbit antisera against a highly conserved 10 amino acid-amidated peptide (kp10) common to all kisspeptin isoforms isolated so far and mapped the distribution of kp10-immunoreactive (ir) cells in the ovine hypothalamus.

    This result measures the body's own Kisspeptin-10. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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