Carnosine and anserine ingestion enhances contribution of nonbicarbonate buffering.

Suzuki Y, Nakao T, Maemura H, Sato M, Kamahara K, Morimatsu F, Takamatsu K

Medicine and science in sports and exercise1 Feb 2006Cited by 20 (Europe PMC)

PMID16531904DOI10.1249/01.mss.0000185108.63028.04PepBankPUB-16531904

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study7

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone7

In this study, L-carnosine was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking L-carnosine.

01HumanNot a test of L-carnosine aloneNon-randomized trialPharmacokinetics
In male participants, CBEX supplementation significantly increased anserine concentration from rest after 30 minutes.
In plain wordsIn male participants, chicken breast extract significantly increased blood anserine from resting levels.
Peptide
L-carnosine
Outcome
IncreaseBlood anserine concentration
Study
n = 8
Comparator
rest
Outcome group
Pharmacokinetics · Pharmacology
Source sentences
Summary
Concentrations of anserine and its related amino acid significantly increased 30 min after CBEX supplementation, as compared with their values at rest.
3 context sentences(design, population, supporting numbers)
Summary · context
The purpose of the present study was to investigate the effect of supplementation with chicken breast extract (CBEX), which was a rich source of carnosine and anserine, on acid-base balance and performance during intense intermittent exercise.
Summary · context
Eight male subjects performed intense intermittent exercise that consisted of 10 x 5-s maximal cycle ergometer sprints with a 25-s recovery period between each sprint.
Summary · context
The subjects ingested 190 g of the test soup containing either CBEX or a placebo 30 min before the commencement of exercise.
In this study, L-carnosine was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking L-carnosine.
Report a problemFND-1653190401
02HumanNot a test of L-carnosine aloneNon-randomized trialPharmacokinetics
In male participants, CBEX supplementation significantly increased the anserine-related amino acid concentration from rest after 30 minutes.
In plain wordsIn male participants, chicken breast extract significantly increased the anserine-related amino acid concentration from resting levels.
Peptide
L-carnosine
Outcome
IncreaseAnserine-related amino acid concentration
Study
n = 8
Comparator
rest
Outcome group
Pharmacokinetics · Pharmacology
Source sentences
Summary
Concentrations of anserine and its related amino acid significantly increased 30 min after CBEX supplementation, as compared with their values at rest.
3 context sentences(design, population, supporting numbers)
Summary · context
The purpose of the present study was to investigate the effect of supplementation with chicken breast extract (CBEX), which was a rich source of carnosine and anserine, on acid-base balance and performance during intense intermittent exercise.
Summary · context
Eight male subjects performed intense intermittent exercise that consisted of 10 x 5-s maximal cycle ergometer sprints with a 25-s recovery period between each sprint.
Summary · context
The subjects ingested 190 g of the test soup containing either CBEX or a placebo 30 min before the commencement of exercise.
In this study, L-carnosine was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking L-carnosine.
Report a problemFND-1653190402
03HumanNot a test of L-carnosine aloneNon-randomized trialPharmacokinetics
In male participants, CBEX supplementation did not significantly increase blood carnosine from rest.
In plain wordsIn male participants, chicken breast extract did not significantly increase blood carnosine from resting levels.
Peptide
L-carnosine
Outcome
No significant changeBlood carnosine concentration
Study
n = 8
Comparator
rest
Outcome group
Pharmacokinetics · Pharmacology
Source sentences
Summary
However, carnosine did not increase significantly.
4 context sentences(design, population, supporting numbers)
Summary · context
Concentrations of anserine and its related amino acid significantly increased 30 min after CBEX supplementation, as compared with their values at rest.
Summary · context
The purpose of the present study was to investigate the effect of supplementation with chicken breast extract (CBEX), which was a rich source of carnosine and anserine, on acid-base balance and performance during intense intermittent exercise.
Summary · context
Eight male subjects performed intense intermittent exercise that consisted of 10 x 5-s maximal cycle ergometer sprints with a 25-s recovery period between each sprint.
Summary · context
The subjects ingested 190 g of the test soup containing either CBEX or a placebo 30 min before the commencement of exercise.
In this study, L-carnosine was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking L-carnosine.
Report a problemFND-1653190403
04HumanNot a test of L-carnosine aloneNon-randomized trialEfficacy outcome
In male participants, blood pH was significantly higher at the end of exercise following CBEX supplementation.
In plain wordsIn male participants, blood pH was significantly higher at exercise completion after chicken breast extract supplementation.
Peptide
L-carnosine
Outcome
IncreaseBlood pH
Study
n = 8
Outcome group
Electrolyte balance · Whole body
Source sentences
Summary
Following CBEX supplementation, the pH was significantly higher (P < 0.05) at the end of exercise, and [HCO3-] was also significantly higher (P < 0.05) during the latter half of exercise and after exercise.
3 context sentences(design, population, supporting numbers)
Summary · context
The purpose of the present study was to investigate the effect of supplementation with chicken breast extract (CBEX), which was a rich source of carnosine and anserine, on acid-base balance and performance during intense intermittent exercise.
Summary · context
Eight male subjects performed intense intermittent exercise that consisted of 10 x 5-s maximal cycle ergometer sprints with a 25-s recovery period between each sprint.
Summary · context
The subjects ingested 190 g of the test soup containing either CBEX or a placebo 30 min before the commencement of exercise.
In this study, L-carnosine was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking L-carnosine.
Report a problemFND-1653190404
05HumanNot a test of L-carnosine aloneNon-randomized trialEfficacy outcome
In male participants, bicarbonate was significantly higher during later exercise and after exercise following CBEX supplementation.
In plain wordsIn male participants, blood bicarbonate was significantly higher during later exercise and after exercise following chicken breast extract supplementation.
Peptide
L-carnosine
Outcome
IncreaseBlood bicarbonate concentration
Study
n = 8
Outcome group
Electrolyte balance · Whole body
Source sentences
Summary
Following CBEX supplementation, the pH was significantly higher (P < 0.05) at the end of exercise, and [HCO3-] was also significantly higher (P < 0.05) during the latter half of exercise and after exercise.
3 context sentences(design, population, supporting numbers)
Summary · context
The purpose of the present study was to investigate the effect of supplementation with chicken breast extract (CBEX), which was a rich source of carnosine and anserine, on acid-base balance and performance during intense intermittent exercise.
Summary · context
Eight male subjects performed intense intermittent exercise that consisted of 10 x 5-s maximal cycle ergometer sprints with a 25-s recovery period between each sprint.
Summary · context
The subjects ingested 190 g of the test soup containing either CBEX or a placebo 30 min before the commencement of exercise.
In this study, L-carnosine was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking L-carnosine.
Report a problemFND-1653190405
06HumanNot a test of L-carnosine aloneNon-randomized trialEfficacy outcome
In male participants, CBEX did not significantly change total power compared with placebo.
In plain wordsIn male participants, chicken breast extract did not significantly change total exercise power compared with placebo.
Peptide
L-carnosine
Outcome
No significant changeTotal power
Study
n = 8
Comparator
placebo
Outcome group
Exercise and physical function · Musculoskeletal
Source sentences
Summary
There were no significant differences in the total power and mean power of each set between the CBEX and placebo supplemented groups.
3 context sentences(design, population, supporting numbers)
Summary · context
The purpose of the present study was to investigate the effect of supplementation with chicken breast extract (CBEX), which was a rich source of carnosine and anserine, on acid-base balance and performance during intense intermittent exercise.
Summary · context
Eight male subjects performed intense intermittent exercise that consisted of 10 x 5-s maximal cycle ergometer sprints with a 25-s recovery period between each sprint.
Summary · context
The subjects ingested 190 g of the test soup containing either CBEX or a placebo 30 min before the commencement of exercise.
In this study, L-carnosine was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking L-carnosine.
Report a problemFND-1653190406
07HumanNot a test of L-carnosine aloneNon-randomized trialEfficacy outcome
In male participants, CBEX did not significantly change mean power of each set compared with placebo.
In plain wordsIn male participants, chicken breast extract did not significantly change mean power in each exercise set compared with placebo.
Peptide
L-carnosine
Outcome
No significant changeMean power of each set
Study
n = 8
Comparator
placebo
Outcome group
Exercise and physical function · Musculoskeletal
Source sentences
Summary
There were no significant differences in the total power and mean power of each set between the CBEX and placebo supplemented groups.
3 context sentences(design, population, supporting numbers)
Summary · context
The purpose of the present study was to investigate the effect of supplementation with chicken breast extract (CBEX), which was a rich source of carnosine and anserine, on acid-base balance and performance during intense intermittent exercise.
Summary · context
Eight male subjects performed intense intermittent exercise that consisted of 10 x 5-s maximal cycle ergometer sprints with a 25-s recovery period between each sprint.
Summary · context
The subjects ingested 190 g of the test soup containing either CBEX or a placebo 30 min before the commencement of exercise.
In this study, L-carnosine was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking L-carnosine.
Report a problemFND-1653190407

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
27 Oct 2026, 18:20 UTC
Study results updated
Version 1
27 Oct 2026, 16:32 UTC
First added · source update from Europe PMC

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