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Study · Measured the body's own peptide · 2006

4 results

Identification of differentially expressed genes between fetal and adult mouse kidney: candidate gene in kidney development.

Guinobert I, Viltard M, Piquemal D, Elalouf JM, Marti J, Lelièvre-Pégorier M

Nephron. Physiology6 Dec 2005Cited by 9 (Europe PMC)

PMID16340241 (opens in a new tab)DOI10.1159/000090054 (opens in a new tab)PepBankPUB-16340241
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured4

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In mice, Tbeta4 was more highly expressed in fetal kidney than in a published adult kidney library.

    In plain wordsIn mice, the body's own Tbeta4 was higher in fetal kidney than in adult kidney.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseTbeta4 expression in fetal versus adult kidney
    Study

    mousen: not reported in source

    fetal and adult mouse kidney
    Comparator
    Adult kidney library
    Outcome group
    Aging markers · Kidney and urinary

    Source sentences

    Summary
    Among these, we identified several candidate genes and focused on a particular one: thymosin beta4 (Tbeta4), an actin-sequestering protein more highly expressed in fetal kidney.
    1 context sentence
    Summary · context
    To obtain a view of the mouse embryonic kidney transcriptome we used the SADE method, which allows large-scale quantitative gene expression measurements.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In mice, Tbeta4 expression increased throughout kidney development and stayed high during active nephrogenesis.

    In plain wordsIn mice, the body's own Tbeta4 rose during kidney development and stayed high while the kidney formed.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseTbeta4 expression during kidney development
    Study

    mousen: not reported in source

    fetal and adult mouse kidney
    Outcome group
    Aging markers · Kidney and urinary

    Source sentences

    Summary
    Tbeta4 increases throughout the kidney development and remains high during active nephrogenesis.
    1 context sentence
    Summary · context
    To obtain a view of the mouse embryonic kidney transcriptome we used the SADE method, which allows large-scale quantitative gene expression measurements.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Other

    In mice at 18 dpc, Tbeta4 mRNA was localised in differentiating glomeruli.

    In plain wordsIn mice, the body's own Tbeta4 mRNA was found in developing kidney filter structures.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableTbeta4 mRNA location in developing kidney
    Study

    mousen: not reported in source

    fetal and adult mouse kidney
    Outcome group
    Aging markers · Kidney and urinary

    Source sentences

    Summary
    Moreover, the spatial distribution of Tbeta4 mRNA was analysed and reveals that during active nephrogenesis (i.e., 18 dpc) Tbeta4 is localised in differentiating glomeruli.
    1 context sentence
    Summary · context
    To obtain a view of the mouse embryonic kidney transcriptome we used the SADE method, which allows large-scale quantitative gene expression measurements.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  4. 04AnimalEndogenous levelAnimal study (in vivo)Other

    In adult mouse kidney, Tbeta4 remained expressed in podocytes and collecting ducts.

    In plain wordsIn adult mice, the body's own Tbeta4 stayed present in some kidney cell types.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableTbeta4 expression in adult kidney
    Study

    mousen: not reported in source

    fetal and adult mouse kidney
    Outcome group
    Aging markers · Kidney and urinary

    Source sentences

    Summary
    In adult kidney, Tbeta4 remains expressed in podocytes and collecting ducts.
    1 context sentence
    Summary · context
    To obtain a view of the mouse embryonic kidney transcriptome we used the SADE method, which allows large-scale quantitative gene expression measurements.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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