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Study · Observational study · n = 80 · 2005

6 results

Short-term and long-term results of resectoscopic myomectomy with and without pretreatment with GnRH analogs in premenopausal women.

Campo S, Campo V, Gambadauro P

Acta obstetricia et gynecologica Scandinavica1 Aug 2005Cited by 34 (Europe PMC)

PMID16026401 (opens in a new tab)DOI10.1111/j.0001-6349.2005.00690.x (opens in a new tab)PepBankPUB-16026401
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study6

6 results from studies that gave the peptide. 6 results from people.

  1. 01HumanObservational studyEfficacy outcome

    In premenopausal women, triptorelin pretreatment was linked to longer myomectomy surgery than no pretreatment.

    In plain wordsIn premenopausal women, triptorelin pretreatment was linked to longer surgery than no pretreatment.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    IncreaseSurgical time
    Study

    n = 80

    Comparator
    No pretreatment
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    3.75 mg · intramuscular · 2 monthsAs given in this study (human).

    Measurements

    Surgical time
    57.65 min
    triptorelin pretreatment
    Surgical time
    40 min
    no pretreatment

    Source sentences

    Summary
    Surgical time of the pretreated patients (group B) was significantly longer than that of untreated patients (group A 40 +/- 18.06 versus group B 57.65 +/- 29.61 min; P = 0.002).
    2 context sentences
    Summary · context
    Data were collected from 80 consecutive resectoscopic myomectomies performed on premenopausal women.
    Summary · context
    Forty-two patients (52.5%) had not received any preoperative medical treatment and in their case surgery was performed during the early proliferative phase (group A), whereas 38 patients (47.5%) had been treated with 2 months of intramuscular GnRH analog (triptorelin, Decapeptyl 3.75 mg) (group B).
  2. 02HumanObservational studyEfficacy outcome

    In premenopausal women, postoperative stay did not differ significantly between triptorelin pretreatment and no pretreatment.

    In plain wordsIn premenopausal women, hospital stay did not differ significantly between triptorelin pretreatment and no pretreatment.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changePostoperative stay
    Study

    n = 80

    Comparator
    No pretreatment
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    3.75 mg · intramuscular · 2 monthsAs given in this study (human).

    Measurements

    Postoperative stay
    1.15 days
    triptorelin pretreatment
    Postoperative stay
    1.05 days
    no pretreatment

    Source sentences

    Summary
    No significant difference was found between the two groups in the length of postoperative stay (group A 1.05 +/- 0.22 days versus group B 1.15 +/- 0.44).
    2 context sentences
    Summary · context
    Data were collected from 80 consecutive resectoscopic myomectomies performed on premenopausal women.
    Summary · context
    Forty-two patients (52.5%) had not received any preoperative medical treatment and in their case surgery was performed during the early proliferative phase (group A), whereas 38 patients (47.5%) had been treated with 2 months of intramuscular GnRH analog (triptorelin, Decapeptyl 3.75 mg) (group B).
  3. 03HumanObservational studyEfficacy outcome

    In premenopausal women, histopathology found cellular myomas without atypia in three patients in each pretreatment group.

    In plain wordsIn premenopausal women, cellular myomas without atypia occurred in three patients with triptorelin pretreatment and three without pretreatment.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    Not applicableCellular myomas without atypia
    Study

    n = 80

    Comparator
    No pretreatment
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    3.75 mg · intramuscular · 2 monthsAs given in this study (human).

    Measurements

    Cellular myomas without atypia
    3 patients
    triptorelin pretreatment
    Cellular myomas without atypia
    3 patients
    no pretreatment

    Source sentences

    Summary
    Histopathology revealed the presence of cellular myomas, without atypia, in three patients of each group.
    2 context sentences
    Summary · context
    Data were collected from 80 consecutive resectoscopic myomectomies performed on premenopausal women.
    Summary · context
    Forty-two patients (52.5%) had not received any preoperative medical treatment and in their case surgery was performed during the early proliferative phase (group A), whereas 38 patients (47.5%) had been treated with 2 months of intramuscular GnRH analog (triptorelin, Decapeptyl 3.75 mg) (group B).
  4. 04HumanObservational studyEfficacy outcome

    In premenopausal women, bleeding recurrence did not differ significantly between triptorelin pretreatment and no pretreatment.

    In plain wordsIn premenopausal women, recurrent bleeding did not differ significantly between triptorelin pretreatment and no pretreatment.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeAbnormal uterine bleeding recurrence
    Study

    n = 80

    Comparator
    No pretreatment
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    3.75 mg · intramuscular · 2 monthsAs given in this study (human).

    Measurements

    Bleeding recurrence
    26.6%
    triptorelin pretreatment
    Bleeding recurrence
    36.3%
    no pretreatment

    Source sentences

    Summary
    At follow-up, abnormal uterine bleeding occurred in 36.3% of group A patients and in 26.6% of group B patients, but the difference showed no statistical significance (P = 0.57).
    2 context sentences
    Summary · context
    Data were collected from 80 consecutive resectoscopic myomectomies performed on premenopausal women.
    Summary · context
    Forty-two patients (52.5%) had not received any preoperative medical treatment and in their case surgery was performed during the early proliferative phase (group A), whereas 38 patients (47.5%) had been treated with 2 months of intramuscular GnRH analog (triptorelin, Decapeptyl 3.75 mg) (group B).
  5. 05HumanObservational studyEfficacy outcome

    In premenopausal women, myoma recurrence occurred in two triptorelin-pretreated patients and three untreated patients.

    In plain wordsIn premenopausal women, myomas recurred in two patients with triptorelin pretreatment and three without pretreatment.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    Not applicableMyoma recurrence
    Study

    n = 80

    Comparator
    No pretreatment
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    3.75 mg · intramuscular · 2 monthsAs given in this study (human).

    Measurements

    Myoma recurrence
    2 patients
    triptorelin pretreatment
    Myoma recurrence
    3 patients
    no pretreatment

    Source sentences

    Summary
    Five patients of myoma recurrence were observed, three in group A and two in group B.
    2 context sentences
    Summary · context
    Data were collected from 80 consecutive resectoscopic myomectomies performed on premenopausal women.
    Summary · context
    Forty-two patients (52.5%) had not received any preoperative medical treatment and in their case surgery was performed during the early proliferative phase (group A), whereas 38 patients (47.5%) had been treated with 2 months of intramuscular GnRH analog (triptorelin, Decapeptyl 3.75 mg) (group B).
  6. 06HumanObservational studyEfficacy outcome

    In premenopausal women, one patient in each pretreatment group required repeat hysteroscopic surgery.

    In plain wordsIn premenopausal women, repeat surgery was needed by one patient with triptorelin pretreatment and one without pretreatment.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    Not applicableRepeat hysteroscopic surgery
    Study

    n = 80

    Comparator
    No pretreatment
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    3.75 mg · intramuscular · 2 monthsAs given in this study (human).

    Measurements

    Repeat hysteroscopic surgery
    1 patients
    triptorelin pretreatment
    Repeat hysteroscopic surgery
    1 patients
    no pretreatment

    Source sentences

    Summary
    Only two patients, one from each group, required repeat hysteroscopic surgery.
    2 context sentences
    Summary · context
    Data were collected from 80 consecutive resectoscopic myomectomies performed on premenopausal women.
    Summary · context
    Forty-two patients (52.5%) had not received any preoperative medical treatment and in their case surgery was performed during the early proliferative phase (group A), whereas 38 patients (47.5%) had been treated with 2 months of intramuscular GnRH analog (triptorelin, Decapeptyl 3.75 mg) (group B).

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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