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Study · Animal study (in vivo) · rat · 2005

3 results

[Long-lasting behavioral effects of chronic neonatal treatment with ACTH (4-10) analogue semax in white rat pups].

Sebentsova EA, Denisenko AV, Levitskaia NG, Andreeva LA, Kamenskiĭ AA, Miasoedov NF

Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova1 Mar 2005Cited by 3 (Europe PMC)

PMID15895862 (opens in a new tab)PepBankPUB-15895862
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rat pups treated daily on postnatal days 8-21, semax increased exploratory activity at the age of four to eight weeks.

    In plain wordsIn rats, semax given after birth raised exploring behaviour at four to eight weeks of age.

    Peptide
    Semax
    Outcome
    IncreaseExploratory activity
    Study

    ratn: not reported in source

    Outcome group
    Anxiety and mood · Nervous system and cognition
    Studied dose
    0.05 mg/kg · intraperitoneal · daily on postnatal days 8-21As given in this study (rat).

    Source sentences

    Summary
    At the age of four to eight weeks, Semax-treated rats displayed elevated exploratory activity, decreased anxiety level and improved passive avoidance conditioning.
    2 context sentences
    Summary · context
    The work was carried out in white rat pups.
    Summary · context
    The peptide (0.05 mg/kg, i/p) was injected daily on the 8th-21st postnatal days.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rat pups treated daily on postnatal days 8-21, semax decreased the anxiety level at the age of four to eight weeks.

    In plain wordsIn rats, semax given after birth lowered anxiety at four to eight weeks of age.

    Peptide
    Semax
    Outcome
    DecreaseAnxiety level
    Study

    ratn: not reported in source

    Outcome group
    Anxiety and mood · Mental health and mood
    Studied dose
    0.05 mg/kg · intraperitoneal · daily on postnatal days 8-21As given in this study (rat).

    Source sentences

    Summary
    At the age of four to eight weeks, Semax-treated rats displayed elevated exploratory activity, decreased anxiety level and improved passive avoidance conditioning.
    2 context sentences
    Summary · context
    The work was carried out in white rat pups.
    Summary · context
    The peptide (0.05 mg/kg, i/p) was injected daily on the 8th-21st postnatal days.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In rat pups treated daily on postnatal days 8-21, semax improved passive avoidance conditioning at the age of four to eight weeks.

    In plain wordsIn rats, semax given after birth improved learning of an avoidance task at four to eight weeks of age.

    Peptide
    Semax
    Outcome
    IncreasePassive avoidance conditioning
    Study

    ratn: not reported in source

    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    0.05 mg/kg · intraperitoneal · daily on postnatal days 8-21As given in this study (rat).

    Source sentences

    Summary
    At the age of four to eight weeks, Semax-treated rats displayed elevated exploratory activity, decreased anxiety level and improved passive avoidance conditioning.
    2 context sentences
    Summary · context
    The work was carried out in white rat pups.
    Summary · context
    The peptide (0.05 mg/kg, i/p) was injected daily on the 8th-21st postnatal days.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    27 Oct 2026, 16:35 UTC

    Study data updated · source update from Europe PMC

  2. Version 2

    12 Oct 2026, 17:28 UTC

    Study results updated

  3. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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