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Study · Not a test of the peptide alone · 2005

8 results

Single and repeated GnRH agonist stimulation tests compared with basal markers of ovarian reserve in the prediction of outcome in IVF.

Hendriks DJ, Broekmans FJ, Bancsi LF, Looman CW, de Jong FH, te Velde ER

Journal of assisted reproduction and genetics1 Feb 2005Cited by 19 (Europe PMC)

PMID15844731 (opens in a new tab)PMCIDPMC3455479 (opens in a new tab)DOI10.1007/s10815-005-1495-3 (opens in a new tab)PepBankPUB-15844731
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study8

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone8

In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Triptorelin (Trelstar, Decapeptyl).

  1. 01HumanNot a test of Triptorelin (Trelstar, Decapeptyl) aloneObservational studyOther

    In women undergoing IVF assessment, GAST variables differed significantly between poor and normal ovarian responders.

    In plain wordsIn women undergoing IVF assessment, triptorelin test variables differed between poor and normal ovarian responders.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    Direction not reportedGAST variables by ovarian response
    Study

    n = 57

    Comparator
    Normal responders
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Source sentences

    Summary
    All the basal and GAST variables were significantly different in the poor responders (n = 19) compared to normal responders (n = 38).
    2 context sentences
    Summary · context
    A total of 57 women was included.
    Summary · context
    In a cycle prior to the IVF treatment, on day 3, an antral follicle count (AFC) was performed and blood taken for basal FSH, inhibin B and E2 measurements, followed by a subcutaneous injection of 100 microg triptorelin for the purpose of the GAST.

    In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).

  2. 02HumanNot a test of Triptorelin (Trelstar, Decapeptyl) aloneObservational studyOther

    In women undergoing IVF assessment, the triptorelin test E2 response best predicted poor ovarian response in cycle 2.

    In plain wordsIn women undergoing IVF assessment, the triptorelin test E2 response best predicted poor ovarian response in cycle 2.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    Not applicableCycle 2 E2 response predictive accuracy
    Study

    n = 57

    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Measurements

    ROC AUC
    0.91 AU
    cycle 2 E2 response

    Source sentences

    Summary
    In the univariate analysis on cycle 1 tests the AFC was the best predictor for poor ovarian response, while in cycle 2 the E2 response in the GAST performed best (ROC(AUC) of 0.91 for both).
    2 context sentences
    Summary · context
    A total of 57 women was included.
    Summary · context
    In a cycle prior to the IVF treatment, on day 3, an antral follicle count (AFC) was performed and blood taken for basal FSH, inhibin B and E2 measurements, followed by a subcutaneous injection of 100 microg triptorelin for the purpose of the GAST.

    In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).

  3. 03HumanNot a test of Triptorelin (Trelstar, Decapeptyl) aloneObservational studyOther

    In women undergoing IVF assessment, multivariate analysis selected mean E2 response from repeated triptorelin tests.

    In plain wordsIn women undergoing IVF assessment, repeated triptorelin tests predicted poor ovarian response through mean E2 response.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    Not applicableRepeated GAST predictive accuracy
    Study

    n = 57

    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Measurements

    ROC AUC
    0.91 AU
    repeated GAST

    Source sentences

    Summary
    Mean E2 response was selected in a multivariate analysis of the repeated GAST variables (ROC(AUC) 0.91).
    2 context sentences
    Summary · context
    A total of 57 women was included.
    Summary · context
    In a cycle prior to the IVF treatment, on day 3, an antral follicle count (AFC) was performed and blood taken for basal FSH, inhibin B and E2 measurements, followed by a subcutaneous injection of 100 microg triptorelin for the purpose of the GAST.

    In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).

  4. 04HumanNot a test of Triptorelin (Trelstar, Decapeptyl) aloneObservational studyOther

    In women undergoing IVF assessment, models including triptorelin test variables had sensitivity, positive predictive value and false positive rate comparable to the AFC and inhibin B model.

    In plain wordsIn women undergoing IVF assessment, triptorelin test models performed about as well as the AFC and inhibin B model.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeGAST model sensitivity, positive predictive value and false positive rate
    Study

    n = 57

    Comparator
    AFC and inhibin B model
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Measurements

    Sensitivity
    −0.8 ratio
    logistic models including GAST variables at specificity level of -0.90, values as written in source
    Positive predictive value
    −0.82 ratio
    logistic models including GAST variables at specificity level of -0.90, values as written in source
    False positive rate
    −0.18 ratio
    logistic models including GAST variables at specificity level of -0.90, values as written in source

    Source sentences

    Summary
    At a specificity level of -0.90, several logistic models including GAST variables appeared to have a sensitivity (-0.80), positive predictive value (-0.82) and false positive rate (-0.18), comparable to a logistic model containing AFC and inhibin B.
    2 context sentences
    Summary · context
    A total of 57 women was included.
    Summary · context
    In a cycle prior to the IVF treatment, on day 3, an antral follicle count (AFC) was performed and blood taken for basal FSH, inhibin B and E2 measurements, followed by a subcutaneous injection of 100 microg triptorelin for the purpose of the GAST.

    In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).

  5. 05HumanNot a test of Triptorelin (Trelstar, Decapeptyl) aloneObservational studyOther

    In women undergoing IVF assessment, triptorelin test models had positive predictive value comparable to the AFC and inhibin B model.

    In plain wordsIn women undergoing IVF assessment, triptorelin test models had positive predictive value comparable to the AFC and inhibin B model.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeGAST model positive predictive value
    Study

    n = 57

    Comparator
    AFC and inhibin B model
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Measurements

    Positive predictive value
    −0.82 unitless
    GAST logistic models at specificity level -0.90

    Source sentences

    Summary
    At a specificity level of -0.90, several logistic models including GAST variables appeared to have a sensitivity (-0.80), positive predictive value (-0.82) and false positive rate (-0.18), comparable to a logistic model containing AFC and inhibin B.
    2 context sentences
    Summary · context
    A total of 57 women was included.
    Summary · context
    In a cycle prior to the IVF treatment, on day 3, an antral follicle count (AFC) was performed and blood taken for basal FSH, inhibin B and E2 measurements, followed by a subcutaneous injection of 100 microg triptorelin for the purpose of the GAST.

    In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).

  6. 06HumanNot a test of Triptorelin (Trelstar, Decapeptyl) aloneObservational studyOther

    In women undergoing IVF assessment, triptorelin test models had false positive rates comparable to the AFC and inhibin B model.

    In plain wordsIn women undergoing IVF assessment, triptorelin test models had false positive rates comparable to the AFC and inhibin B model.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeGAST model false positive rate
    Study

    n = 57

    Comparator
    AFC and inhibin B model
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Measurements

    False positive rate
    −0.18 unitless
    GAST logistic models at specificity level -0.90

    Source sentences

    Summary
    At a specificity level of -0.90, several logistic models including GAST variables appeared to have a sensitivity (-0.80), positive predictive value (-0.82) and false positive rate (-0.18), comparable to a logistic model containing AFC and inhibin B.
    2 context sentences
    Summary · context
    A total of 57 women was included.
    Summary · context
    In a cycle prior to the IVF treatment, on day 3, an antral follicle count (AFC) was performed and blood taken for basal FSH, inhibin B and E2 measurements, followed by a subcutaneous injection of 100 microg triptorelin for the purpose of the GAST.

    In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).

  7. 07HumanNot a test of Triptorelin (Trelstar, Decapeptyl) aloneObservational studyOther

    In women undergoing IVF assessment, triptorelin test variables showed no significant association with ongoing pregnancy.

    In plain wordsIn women undergoing IVF assessment, triptorelin test variables showed no significant link to ongoing pregnancy.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeAssociation with ongoing pregnancy
    Study

    n = 57

    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Source sentences

    Summary
    None of the test variables showed a significant relation with ongoing pregnancy.
    2 context sentences
    Summary · context
    A total of 57 women was included.
    Summary · context
    In a cycle prior to the IVF treatment, on day 3, an antral follicle count (AFC) was performed and blood taken for basal FSH, inhibin B and E2 measurements, followed by a subcutaneous injection of 100 microg triptorelin for the purpose of the GAST.

    In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).

  8. 08HumanNot a test of Triptorelin (Trelstar, Decapeptyl) aloneObservational studyOther

    In women undergoing IVF assessment, neither single nor repeated GAST outperformed day 3 AFC and inhibin B in predictive accuracy and clinical value.

    In plain wordsIn women undergoing IVF assessment, single and repeated triptorelin tests performed no better than basal follicle count and inhibin B tests.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeSingle and repeated GAST versus basal tests
    Study

    n = 57

    Comparator
    Day 3 AFC and inhibin B
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Source sentences

    Summary
    However, comparing the predictive accuracy and clinical value of the GAST with a day 3 AFC and inhibin B, it appeared that neither a single nor a repeated GAST performed better.
    2 context sentences
    Summary · context
    A total of 57 women was included.
    Summary · context
    In a cycle prior to the IVF treatment, on day 3, an antral follicle count (AFC) was performed and blood taken for basal FSH, inhibin B and E2 measurements, followed by a subcutaneous injection of 100 microg triptorelin for the purpose of the GAST.

    In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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