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Study · Animal study (in vivo) · rat · 2005

4 results

[Dependence of long-lasting effects of the ACTH(4-10) analogue semax on the time of its neonatal administration].

Sebentsova EA, Glazova NIu, Levitskaia NG, Andreeva LA, Alfeeva LIu, Kamenskiĭ AA, Miasoedov NF

Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova1 Feb 2005Cited by 1 (Europe PMC)

PMID15835535 (opens in a new tab)PepBankPUB-15835535
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats, semax injections during the first week of life decreased exploratory activity at 4-8 weeks of age.

    In plain wordsIn rats, semax given in the first week of life lowered exploring behaviour at 4-8 weeks of age.

    Peptide
    Semax
    Outcome
    DecreaseExploratory activity after injections in the first week of life
    Study

    ratn: not reported in source

    Outcome group
    Anxiety and mood · Nervous system and cognition
    Studied dose
    0.05 mg/kg · intraperitoneal · daily during the first week of postnatal developmentAs given in this study (rat).

    Source sentences

    Summary
    peptide injections during the first week lead to a decrease
    1 context sentence
    Summary · context
    The peptide was injected daily intraperitoneally in dose 0.05 mg/kg during the first, second or second-third weeks of postnatal development.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats, semax injections during the second or second-third weeks of life increased exploratory activity at 4-8 weeks of age.

    In plain wordsIn rats, semax given in the second or third week of life raised exploring behaviour at 4-8 weeks of age.

    Peptide
    Semax
    Outcome
    IncreaseExploratory activity after injections in the second or second-third weeks of life
    Study

    ratn: not reported in source

    Outcome group
    Anxiety and mood · Nervous system and cognition
    Studied dose
    0.05 mg/kg · intraperitoneal · daily during the second or second-third weeks of postnatal developmentAs given in this study (rat).

    Source sentences

    Summary
    during second or second-third weeks--to an increase of exploratory activity
    1 context sentence
    Summary · context
    The peptide was injected daily intraperitoneally in dose 0.05 mg/kg during the first, second or second-third weeks of postnatal development.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In rats, neonatal semax administration at all tested times diminished anxiety in adulthood.

    In plain wordsIn rats, semax given in the first weeks of life lowered anxiety in adulthood.

    Peptide
    Semax
    Outcome
    DecreaseAnxiety in adult rats
    Study

    ratn: not reported in source

    Outcome group
    Anxiety and mood · Mental health and mood
    Studied dose
    0.05 mg/kg · intraperitoneal · daily during the first, second or second-third weeks of postnatal developmentAs given in this study (rat).

    Source sentences

    Summary
    Furthermore, the peptide adminictration at all times diminished anxiety
    1 context sentence
    Summary · context
    The peptide was injected daily intraperitoneally in dose 0.05 mg/kg during the first, second or second-third weeks of postnatal development.
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In rats, neonatal semax administration at all tested times improved learning ability in adulthood.

    In plain wordsIn rats, semax given in the first weeks of life improved learning ability in adulthood.

    Peptide
    Semax
    Outcome
    IncreaseLearning ability in adult rats
    Study

    ratn: not reported in source

    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    0.05 mg/kg · intraperitoneal · daily during the first, second or second-third weeks of postnatal developmentAs given in this study (rat).

    Source sentences

    Summary
    the peptide adminictration at all times diminished anxiety and improved learning ability of adult rats.
    1 context sentence
    Summary · context
    The peptide was injected daily intraperitoneally in dose 0.05 mg/kg during the first, second or second-third weeks of postnatal development.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    27 Oct 2026, 16:35 UTC

    Study data updated · source update from Europe PMC

  2. Version 2

    12 Oct 2026, 17:28 UTC

    Study results updated

  3. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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