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Study · Measured the body's own peptide · 2004

2 results

[Overexpression of thymosin beta4 in the cochlea of senescence-accelerated mouse].

Wang YS, Asamura K, Usami S

Zhonghua er bi yan hou ke za zhi1 Dec 2004

PMID15813012 (opens in a new tab)PepBankPUB-15813012
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In senescence-accelerated mice, thymosin beta4 expression in the cochlea was higher in old than in young mice, and RT-PCR confirmed the change.

    In plain wordsIn mice, the body's own thymosin beta4 gene was more active in the inner ear of old mice than in young mice.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseThymosin beta4 expression in cochlea of old versus young SAM mice
    Study

    mousen: not reported in source

    Comparator
    Young (2 month) mouse cochlea
    Outcome group
    Aging markers · Aging and longevity

    Source sentences

    Summary
    RT-PCR results confirmed the changes in expression of thymosin beta4 of 3 genes examined.
    2 context sentences
    Title · context
    [Overexpression of thymosin beta4 in the cochlea of senescence-accelerated mouse].
    Summary · context
    Gene micro-array slides containing 1101 mouse genes were hybridized to cDNA micro-arrays (Atlas Glass Array Mouse 1.0) that were synthesized using total RNAs from the cochlea of 2 mounts and 12 mounts mouse.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In the mouse cochlea, thymosin beta4 was located mainly in the tectorial membrane and the supporting cells of the outer hair cell.

    In plain wordsIn mice, the body's own thymosin beta4 was found mainly in the tectorial membrane and the supporting cells of the inner ear.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableLocation of thymosin beta4 protein in the cochlea
    Study

    mousen: not reported in source

    Outcome group
    Aging markers · Aging and longevity

    Source sentences

    Summary
    Through the using of immunofluorescence, it was shown that thymosin beta4 was primarily located in the tectorial membrane and the supporting cells of outer hair cell.
    1 context sentence
    Summary · context
    Gene micro-array slides containing 1101 mouse genes were hybridized to cDNA micro-arrays (Atlas Glass Array Mouse 1.0) that were synthesized using total RNAs from the cochlea of 2 mounts and 12 mounts mouse.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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