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Study · Measured the body's own peptide · 2005

2 results

Phylogenetic analysis and developmental expression of thymosin-beta4 gene in amphioxus.

Huang X, Zhang W, Zhang H

Development genes and evolution24 Mar 2005Cited by 3 (Europe PMC)

PMID15789248 (opens in a new tab)DOI10.1007/s00427-005-0481-1 (opens in a new tab)PepBankPUB-15789248
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In amphioxus, in situ hybridization detected thymosin-beta4 expression in locations homologous to vertebrate expression regions, such as the neural plate, neural tube and somites.

    In plain wordsIn amphioxus, the body's own thymosin-beta4 gene was active in body regions that match where vertebrate embryos use it.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableThymosin-beta4 expression sites in amphioxus embryos and adults
    Study

    Branchiostoma belcheri (amphioxus)n: not reported in source

    Outcome group
    Gene expression · Whole body

    Source sentences

    Summary
    In situ hybridization reveals that the expression is detected in the locations homologous to orthologous genes expressing regions of vertebrate embryos and adults, such as the neural plate, neural tube, paraxial mesoderm, differentiating somites, pharynx and gut, midgut diverticulus, blood vessels and body spaces.
    1 context sentence
    Summary · context
    Here a cDNA for a thymosin-beta4 gene was isolated from the amphioxus, Branchiostoma belcheri.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

Studies that did not test the peptide alone1

In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin beta-4 (human).

  1. 02Computer modelNot a test of Thymosin beta-4 (human) aloneIn silicoOther

    A phylogenetic tree of the deduced amino acid sequence placed the amphioxus gene in the thymosin-beta4 subfamily, split at the base of the vertebrate gene clade.

    In plain wordsIn a computer analysis, the amphioxus gene sequence grouped with thymosin-beta4 genes at the base of the vertebrate branch.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicablePhylogenetic placement of amphioxus thymosin-beta4 gene
    Study

    n: not reported in source

    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    A molecular phylogenetic tree constructed from the deduced amino acid sequence of the isolated cDNA indicates that this gene belongs to the thymosin-beta4 subfamily, but it is split at the base of the vertebrate gene clade in evolution.
    1 context sentence
    Summary · context
    Here a cDNA for a thymosin-beta4 gene was isolated from the amphioxus, Branchiostoma belcheri.

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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