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Study · Animal study (in vivo) · mouse · 2005

3 results

The stable gastric pentadecapeptide BPC 157, given locally, improves CO2 laser healing in mice.

Bilic M, Bumber Z, Blagaic AB, Batelja L, Seiwerth S, Sikiric P

Burns : journal of the International Society for Burn Injuries20 Jan 2005Cited by 23 (Europe PMC)

PMID15774286 (opens in a new tab)DOI10.1016/j.burns.2004.10.013 (opens in a new tab)PepBankPUB-15774286
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In mice with CO2 laser skin injuries, topical BPC‑157 consistently improved healing macroscopically.

    In plain wordsIn mice with laser skin burns, BPC‑157 cream consistently improved healing that could be seen by eye.

    Peptide
    BPC-157
    Outcome
    IncreaseMacroscopic healing of CO2 laser injury
    Study

    mousen: not reported in source

    CO2 laser injury on dorsal skin
    Comparator
    Vehicle only or untreated
    Outcome group
    Wound healing · Skin and wound
    Studied dose
    1 microg, 1 ng or 1 pg/g neutral cream · topicalAs given in this study (mouse).

    Source sentences

    Summary
    BPC 157 consistently improved healing after the CO(2) laser injury, both macroscopically and microscopically.
    1 context sentence
    Summary · context
    Because of the particular healing problems associated with laser use, we have now studied the effect of pentadecapeptide BPC 157 on CO(2) laser injuries (Sharplan 1075 laser: 20 W, distance 12.5 cm, spot size 0.8 mm and exposure time 1s) created on the dorsal skin of anaesthetised male NMRI-Hannover mice.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In mice with CO2 laser skin injuries, topical BPC‑157 consistently improved healing microscopically.

    In plain wordsIn mice with laser skin burns, BPC‑157 cream consistently improved healing seen under the microscope.

    Peptide
    BPC-157
    Outcome
    IncreaseMicroscopic healing of CO2 laser injury
    Study

    mousen: not reported in source

    CO2 laser injury on dorsal skin
    Comparator
    Vehicle only or untreated
    Outcome group
    Wound healing · Skin and wound
    Studied dose
    1 microg, 1 ng or 1 pg/g neutral cream · topicalAs given in this study (mouse).

    Source sentences

    Summary
    BPC 157 consistently improved healing after the CO(2) laser injury, both macroscopically and microscopically.
    1 context sentence
    Summary · context
    Because of the particular healing problems associated with laser use, we have now studied the effect of pentadecapeptide BPC 157 on CO(2) laser injuries (Sharplan 1075 laser: 20 W, distance 12.5 cm, spot size 0.8 mm and exposure time 1s) created on the dorsal skin of anaesthetised male NMRI-Hannover mice.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In mice with CO2 laser skin injuries, an ointment of 1 microg BPC‑157 per g neutral cream was effective.

    In plain wordsIn mice with laser skin burns, a cream with BPC‑157 worked, without a special carrier.

    Peptide
    BPC-157
    Outcome
    IncreaseEffectiveness of ointment with 1 microg BPC 157 per g
    Study

    mousen: not reported in source

    CO2 laser injury on dorsal skin
    Comparator
    Vehicle only or untreated
    Outcome group
    Wound healing · Skin and wound
    Studied dose
    1 microg/g neutral cream · topicalAs given in this study (mouse).

    Source sentences

    Summary
    The effect was produced with a simple method of application and favourable peptide stability (no carrier), and confirms the effectiveness of an ointment containing 1 microg BPC 157 (dissolved in saline)/g neutral cream.
    1 context sentence
    Summary · context
    Because of the particular healing problems associated with laser use, we have now studied the effect of pentadecapeptide BPC 157 on CO(2) laser injuries (Sharplan 1075 laser: 20 W, distance 12.5 cm, spot size 0.8 mm and exposure time 1s) created on the dorsal skin of anaesthetised male NMRI-Hannover mice.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    10 Oct 2026, 08:19 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:56 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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