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Study · Not a test of the peptide alone · 2005

2 results

Targeted biomarker detection via whole protein ion trap tandem mass spectrometry: thymosin beta4 in a human lung cancer cell line.

Yan F, He M, Hogan JM, Rossie SS, McLuckey SA

Journal of mass spectrometry : JMS1 Apr 2005Cited by 1 (Europe PMC)

PMID15712244 (opens in a new tab)DOI10.1002/jms.797 (opens in a new tab)PepBankPUB-15712244
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin beta-4 (human).

  1. 01LabNot a test of Thymosin beta-4 (human) aloneIn vitro (cells)Other

    Ion trap tandem mass spectrometry at the whole protein level identified N-terminally acetylated thymosin beta4 in a human lung cancer cell line.

    In plain wordsIn lab tests on a human lung cancer cell line, a mass spectrometry method identified thymosin beta4.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableIdentification of N-terminally acetylated thymosin beta4 by ion trap tandem mass spectrometry
    Study

    humann: not reported in source

    human lung cancer cell line
    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    N-Terminally acetylated thymosin beta4, a species implicated for use as a cancer biomarker, was identified in a human lung cancer cell line using ion trap tandem mass spectrometry at the whole protein level.
    1 context sentence
    Summary · context
    Ion-ion proton transfer reactions were used for parent ion concentration/manipulation and to simplify interpretation of product ion spectra.

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

  2. 02LabNot a test of Thymosin beta-4 (human) aloneIn vitro (cells)Other

    Each selected charge state of thymosin beta4 gave enough fragmentation data for confident identification in a complex protein mixture.

    In plain wordsIn lab tests, every charge state of thymosin beta4 gave enough data to detect it in a complex mixture.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableSpecificity of detection by any parent ion charge state
    Study

    humann: not reported in source

    human lung cancer cell line
    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    Each parent ion charge state selected, however, provided sufficient information to make a confident identification. Furthermore, each charge state provided relatively rich fragmentation. Therefore, any of the charge states can be used to detect with high specificity thymosin beta(4) in a complex protein mixture.
    1 context sentence
    Summary · context
    Ion-ion proton transfer reactions were used for parent ion concentration/manipulation and to simplify interpretation of product ion spectra.

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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