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Study · Animal study (in vivo) · cba mice, broiler chickens (not split) and broiler chickens · 1998

3 results

Immuno-, phagocytosis-modulating, and antitoxic properties of amino acids and peptide preparations.

Belokrylov GA, Derevnina OY, Molchanova IV, Sorochinskaya EI

Drug development and industrial pharmacy1 Feb 1998Cited by 5 (Europe PMC)

PMID15605441 (opens in a new tab)DOI10.3109/03639049809085596 (opens in a new tab)PepBankPUB-15605441
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In mice and chickens, thymosin alpha‑1 stimulated the immune response only at the site of subcutaneous injection.

    In plain wordsIn mice and chickens, thymosin alpha‑1 boosted the immune response only when injected under the skin at the site.

    Peptide
    Thymosin alpha-1
    Outcome
    IncreaseImmune response to SRBC
    Study

    CBA mice and broiler chickens (not split)n: not reported in source

    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated · subcutaneousAs given in this study (CBA mice and broiler chickens (not split)).

    Source sentences

    Summary
    The peptides thymopentin, thymosin alpha-1, and peptide mixtures (thymosin fraction 5, thymalin) stimulate the immune response only at the site of subcutaneous injections.
    1 context sentence
    Summary · context
    The influence of amino acids, their mixtures, and peptides on the immune response, phagocytosis in vitro, and in CBA mice, and broiler chickens, as well as on in vitro ability of listed preparations to protect animals' splenocytes from toxic action of benzene and aflatoxin B1 were studied.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In the studied animals, thymalin did not change the immune response to Viantigen.

    In plain wordsIn mice and chickens studied, thymalin did not change the immune response to Viantigen.

    Peptide
    Thymalin
    Outcome
    No significant changeImmune response to Viantigen
    Study

    CBA mice and broiler chickensn: not reported in source

    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    None of the preparations studied change the immune response to Viantigen.
    2 context sentences
    Summary · context
    The peptides thymopentin, thymosin alpha-1, and peptide mixtures (thymosin fraction 5, thymalin) stimulate the immune response only at the site of subcutaneous injections.
    Summary · context
    The influence of amino acids, their mixtures, and peptides on the immune response, phagocytosis in vitro, and in CBA mice, and broiler chickens, as well as on in vitro ability of listed preparations to protect animals' splenocytes from toxic action of benzene and aflatoxin B1 were studied.

Studies that did not test the peptide alone1

In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin alpha-1.

  1. 03AnimalNot a test of Thymosin alpha-1 aloneAnimal study (in vivo)Efficacy outcome

    In mice and chickens, none of the studied preparations, including thymosin alpha‑1, changed the immune response to Vi antigen.

    In plain wordsIn mice and chickens, none of the tested preparations, including thymosin alpha‑1, changed the immune response to Vi antigen.

    Peptide
    Thymosin alpha-1
    Outcome
    No significant changeImmune response to Vi antigen
    Study

    CBA mice and broiler chickens (not split)n: not reported in source

    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    None of the preparations studied change the immune response to Viantigen.
    1 context sentence
    Summary · context
    The influence of amino acids, their mixtures, and peptides on the immune response, phagocytosis in vitro, and in CBA mice, and broiler chickens, as well as on in vitro ability of listed preparations to protect animals' splenocytes from toxic action of benzene and aflatoxin B1 were studied.

    In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Versions 5 to 15Current

    28 Oct 2026, 02:02 UTC

    The same notice was added 11 times, first on 14 Oct 2026, 05:02 UTC. The status did not change between them.

    Study results updated

  2. Version 4

    14 Oct 2026, 01:46 UTC

    Study data updated · source update from Europe PMC

  3. Version 3

    10 Oct 2026, 08:55 UTC

    Study results updated

  4. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  5. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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