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Study · Randomized controlled trial · n = 40 · 2004

5 results

An open and randomized study comparing the efficacy of standard danazol and modified triptorelin regimens for postoperative disease management of moderate to severe endometriosis.

Wong AY, Tang L

Fertility and sterility1 Jun 2004Cited by 18 (Europe PMC)

PMID15193471 (opens in a new tab)DOI10.1016/j.fertnstert.2003.12.020 (opens in a new tab)PepBankPUB-15193471
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. 5 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In patients with endometriosis, pain control was similar with triptorelin and danazol.

    In plain wordsIn patients with endometriosis, pain control was similar with triptorelin and danazol.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changePain control
    Study

    n = 40

    Comparator
    Danazol
    Outcome group
    Pain · Reproductive and sexual health
    Studied dose
    Dose not stated · 6 monthsAs given in this study (human).

    Source sentences

    Summary
    Pain control was similar between danazol and triptorelin therapy.
    3 context sentences
    Summary · context
    Open and randomized trial.
    Summary · context
    Forty patients after their first conservative operation for endometriosis, with surgical confirmation of revised AFS stage III or IV endometriosis.
    Summary · context
    Postoperative 6 months' therapy of danazol or triptorelin every 6 weeks, postmedical therapy second-look laparoscopy.
  2. 02HumanRandomized controlled trialSafety outcome

    In patients with endometriosis, triptorelin caused less breakthrough bleeding than danazol.

    In plain wordsIn patients with endometriosis, triptorelin caused less breakthrough bleeding than danazol.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    DecreaseBreakthrough bleeding
    Study

    n = 40

    Comparator
    Danazol
    Outcome group
    Adverse events · Reproductive and sexual health
    Studied dose
    Dose not stated · 6 monthsAs given in this study (human).

    Source sentences

    Summary
    There was less breakthrough bleeding with triptorelin.
    3 context sentences
    Summary · context
    Open and randomized trial.
    Summary · context
    Forty patients after their first conservative operation for endometriosis, with surgical confirmation of revised AFS stage III or IV endometriosis.
    Summary · context
    Postoperative 6 months' therapy of danazol or triptorelin every 6 weeks, postmedical therapy second-look laparoscopy.
  3. 03HumanRandomized controlled trialSafety outcome

    In patients with endometriosis, fewer patients discontinued triptorelin than danazol because of side effects.

    In plain wordsIn patients with endometriosis, fewer patients discontinued triptorelin than danazol because of side effects.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    DecreaseTreatment discontinuation due to side effects
    Study

    n = 40

    Comparator
    Danazol
    Outcome group
    Adverse events · Reproductive and sexual health
    Studied dose
    Dose not stated · 6 monthsAs given in this study (human).

    Source sentences

    Summary
    More patients failed to complete the whole course of danazol because of its side effects.
    3 context sentences
    Summary · context
    Open and randomized trial.
    Summary · context
    Forty patients after their first conservative operation for endometriosis, with surgical confirmation of revised AFS stage III or IV endometriosis.
    Summary · context
    Postoperative 6 months' therapy of danazol or triptorelin every 6 weeks, postmedical therapy second-look laparoscopy.
  4. 04HumanRandomized controlled trialEfficacy outcome

    In patients with endometriosis, revised AFS scores did not differ significantly between triptorelin and danazol.

    In plain wordsIn patients with endometriosis, revised AFS scores did not differ significantly between triptorelin and danazol.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeRevised AFS score
    Study

    n = 40

    Comparator
    Danazol
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated · 6 monthsAs given in this study (human).

    Source sentences

    Summary
    The revised AFS score at second-look laparoscopy did not show a significant difference between the two medications.
    3 context sentences
    Summary · context
    Open and randomized trial.
    Summary · context
    Forty patients after their first conservative operation for endometriosis, with surgical confirmation of revised AFS stage III or IV endometriosis.
    Summary · context
    Postoperative 6 months' therapy of danazol or triptorelin every 6 weeks, postmedical therapy second-look laparoscopy.
  5. 05HumanRandomized controlled trialEfficacy outcome

    In patients with endometriosis, triptorelin injections every six weeks adequately suppressed pituitary function.

    In plain wordsIn patients with endometriosis, triptorelin injections every six weeks adequately suppressed pituitary function.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    DecreasePituitary suppression
    Study

    n: not reported in source

    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated · 6 monthsAs given in this study (human).

    Source sentences

    Summary
    Adequate pituitary suppression was observed with injection of triptorelin every 6 weeks.
    3 context sentences
    Summary · context
    Open and randomized trial.
    Summary · context
    Forty patients after their first conservative operation for endometriosis, with surgical confirmation of revised AFS stage III or IV endometriosis.
    Summary · context
    Postoperative 6 months' therapy of danazol or triptorelin every 6 weeks, postmedical therapy second-look laparoscopy.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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