Skip to content

Study · Measured the body's own peptide · 2003

2 results

Up-regulation of thymosin beta 4 gene expression in experimentally-induced uterine adenomyosis in mice.

Kawahara R, Matsuda M, Imaoka T, Mori T

In vivo (Athens, Greece)1 Nov 2003Cited by 2 (Europe PMC)

PMID14758721 (opens in a new tab)PepBankPUB-14758721
Publisher pageAsk about this study
Jump to 2 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In mice with pituitary graft-induced uterine adenomyosis, thymosin beta‑4 was abundant in the adenomyotic uteri, which confirmed its up-regulation in the subtractive library.

    In plain wordsIn mice with induced uterine adenomyosis, the body's own thymosin beta‑4 was abundant in the affected uteri.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseTb4 abundance in adenomyotic uteri
    Study

    mousen: not reported in source

    Pituitary graft-induced uterine adenomyosis
    Outcome group
    Gene expression · Reproductive and sexual health

    Source sentences

    Summary
    Thymosin beta 4 (Tb4), an actin sequestering protein, was contained in the library and was confirmed to be abundant in the adenomyotic uteri.
    1 context sentence
    Summary · context
    A subtractive cDNA library that contained genes up-regulated in the uterus with adenomyosis induced by pituitary grafting was constructed in mice.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In mice with uterine adenomyosis, Tb4 immunoreactivity was present in the myometrium and stronger close to the tip of the invading endometrial tissue.

    In plain wordsIn mice with uterine adenomyosis, the body's own Tb4 showed a stronger signal in muscle tissue near the invading endometrium.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseTb4 immunoreactivity in myometrium
    Study

    mousen: not reported in source

    Pituitary graft-induced uterine adenomyosis
    Outcome group
    Gene expression · Reproductive and sexual health

    Source sentences

    Summary
    Tb4-immunoreactivity was shown in the myometrium, with a stronger signal being observed in the area closer to the tip of endometrial tissue that is invading the myometrium.
    1 context sentence
    Summary · context
    A subtractive cDNA library that contained genes up-regulated in the uterus with adenomyosis induced by pituitary grafting was constructed in mice.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.