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Study · Measured the body's own peptide · 2003

1 result

Use of ProteinChip array surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS) to identify thymosin beta-4, a differentially secreted protein from lymphoblastoid cell lines.

Diamond DL, Zhang Y, Gaiger A, Smithgall M, Vedvick TS, Carter D

Journal of the American Society for Mass Spectrometry1 Jul 2003Cited by 18 (Europe PMC)

PMID12837598 (opens in a new tab)DOI10.1016/s1044-0305(03)00265-4 (opens in a new tab)PepBankPUB-12837598
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelIn vitro (cells)Other

    A mass peak at m/z 4972.1, identified as thymosin beta‑4, was highly over-represented in secretions of the Epstein-Barr virus transformed B-cell line compared with normal B-cells.

    In plain wordsCells transformed by Epstein-Barr virus released more of their own thymosin beta‑4 than normal B-cells did.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseSecretion of thymosin beta-4 by transformed versus normal B-cells
    Study

    humann: not reported in source

    Normal B-cells and Epstein-Barr virus transformed B-cell line (LCL)
    Comparator
    Normal B-cells
    Outcome group
    Tumor growth · Cancer

    Measurements

    Mass peak
    4972.1 m/z
    transformed B-cell line

    Source sentences

    Summary
    A mass peak at m/z = 4972.1 that was highly over-represented in the transformed B-cell line was chosen for identification and purified by reversed phase chromatography with concomitant monitoring of fractions by SELDI-TOF MS.
    2 context sentences
    Summary · context
    Fragment matching of the resulting peptides identified the protein as thymosin beta-4.
    Summary · context
    Mass spectra of the range of proteins secreted from normal B-cells were generated along with those secreted from Epstein-Barr virus transformed B-cells.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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