Skip to content

Study · Randomized controlled trial · n = 100 · 2003

3 results

Gonadotropin-releasing hormone agonist treatment before abdominal myomectomy: a controlled trial.

Vercellini P, Trespìdi L, Zaina B, Vicentini S, Stellato G, Crosignani PG

Fertility and sterility1 Jun 2003Cited by 34 (Europe PMC)

PMID12798887 (opens in a new tab)DOI10.1016/s0015-0282(03)00362-5 (opens in a new tab)PepBankPUB-12798887
Publisher pagePubMedAsk about this study
Jump to 3 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In women undergoing myomectomy, preoperative triptorelin did not significantly reduce blood loss compared with immediate surgery.

    In plain wordsIn women undergoing myomectomy, preoperative triptorelin did not significantly reduce blood loss compared with immediate surgery.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeIntraoperative blood loss
    Study

    n = 100

    Comparator
    Immediate surgery
    Analysis
    Primary
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated · 8 weeksAs given in this study (human).

    Measurements

    Blood loss
    265 mL
    triptorelin
    Blood loss
    296 mL
    immediate surgery
    Mean difference in blood loss
    −31 mL
    triptorelin minus immediate surgery

    Source sentences

    Summary
    Mean (+/-SD) intraoperative blood loss was 265 +/- 181 mL in triptorelin recipients and 296 +/- 204 in patients who had immediate surgery (mean difference, -31 mL [95% CI, -108 to 46 mL]).
    3 context sentences
    Summary · context
    Randomized controlled trial.
    Summary · context
    One hundred premenopausal women requiring first-line conservative surgery for symptomatic intramural or subserous fibroids.
    Summary · context
    Eight weeks of treatment with depot triptorelin before myomectomy or immediate surgery.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In women undergoing myomectomy, most procedures had routine difficulty with either preoperative triptorelin or immediate surgery.

    In plain wordsIn women undergoing myomectomy, most procedures had routine difficulty with either preoperative triptorelin or immediate surgery.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    Not applicableProcedure difficulty
    Study

    n = 100

    Comparator
    Immediate surgery
    Analysis
    Primary
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated · 8 weeksAs given in this study (human).

    Source sentences

    Summary
    Most procedures in either group were of routine difficulty.
    3 context sentences
    Summary · context
    Randomized controlled trial.
    Summary · context
    One hundred premenopausal women requiring first-line conservative surgery for symptomatic intramural or subserous fibroids.
    Summary · context
    Eight weeks of treatment with depot triptorelin before myomectomy or immediate surgery.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In women undergoing myomectomy, four triptorelin recipients and one immediate-surgery recipient had recurrence on ultrasonography six months later.

    In plain wordsIn women undergoing myomectomy, four triptorelin recipients and one immediate-surgery recipient had recurrence on ultrasound six months later.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    IncreaseFibroid recurrence
    Study

    n = 100

    Comparator
    Immediate surgery
    Analysis
    Primary
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated · 8 weeksAs given in this study (human).

    Measurements

    Fibroid recurrence
    4 women
    triptorelin
    Fibroid recurrence
    1 women
    immediate surgery

    Source sentences

    Summary
    On ultrasonography 6 months after myomectomy, four women in the GnRH agonist group and one in the immediate surgery group had tumor recurrence.
    3 context sentences
    Summary · context
    Randomized controlled trial.
    Summary · context
    One hundred premenopausal women requiring first-line conservative surgery for symptomatic intramural or subserous fibroids.
    Summary · context
    Eight weeks of treatment with depot triptorelin before myomectomy or immediate surgery.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.