In healthy volunteers, the pharmacodynamic model showed a dose-proportional effect of NN2211 (liraglutide) on the parameters that control beta-cell insulin secretion.
In plain wordsIn healthy volunteers, liraglutide had an effect on insulin release that grew in proportion to the dose.
- Peptide
- Liraglutide
- Outcome
- Direction not reportedBeta-cell insulin secretion parameters
- Study
n: not reported in source
- Comparator
- Placebo
- Outcome group
- Glycemic control · Endocrine and hormones
- Studied dose
- eight dose levels (values not stated)As given in this study (human).
Source sentences
The analysis demonstrated a dose proportional effect of NN2211 on the parameters controlling beta cell insulin secretion.
2 context sentences(design, population, supporting numbers)
In the present study, eight dose levels of NN2211 were tested in healthy human volunteers.
Placebo-dosed subjects were included in the analysis.