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Study · Measured the body's own peptide · 2002

4 results

Age-related changes of thymalin content in human epidermis.

Khlystova ZS, Kalinina II, Shmeleva SP, Ryabchikov OP, Khavinson VKh

Bulletin of experimental biology and medicine1 Jun 2002Cited by 1 (Europe PMC)

PMID12447484 (opens in a new tab)DOI10.1023/a:1020214816056 (opens in a new tab)PepBankPUB-12447484
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured4

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelEx vivo tissueOther

    Immunomorphological analysis detected natural thymalin in human epidermis and fetal reticuloepithelium.

    In plain wordsIn lab tests, the body's own thymalin was present in human epidermis and fetal reticuloepithelium.

    Peptide
    Thymalin
    Outcome
    Not applicableThymalin presence in epidermis and fetal reticuloepithelium
    Study

    humann: not reported in source

    Human epidermis and fetal reticuloepithelium
    Outcome group
    Receptor activity and mechanism · Skin and wound

    Source sentences

    Summary
    Immunomorphological analysis revealed the presence of thymalin in human epidermis and in fetal reticuloepithelium.

    This result measures the body's own Thymalin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02LabEndogenous levelEx vivo tissueOther

    In human embryos and adults, natural thymalin was present only in young epidermal cells that undergo age-related involution.

    In plain wordsIn lab tests, natural thymalin occurred only in young human epidermal cells, which showed age-related involution.

    Peptide
    Thymalin
    Outcome
    Not applicableYoung epidermal cell thymalin localization
    Study

    humann: not reported in source

    Human epidermis and fetal reticuloepithelium
    Outcome group
    Aging markers · Skin and wound

    Source sentences

    Summary
    In embryos and adult humans thymalin is present only in young epidermal cells, which undergo age-related involution.

    This result measures the body's own Thymalin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03LabEndogenous levelEx vivo tissueOther

    In human epidermis at 70 years, the layer of cells containing natural thymalin appeared thinned and discontinuous.

    In plain wordsIn lab tests, the skin layer containing the body's own thymalin appeared thin and discontinuous at 70 years.

    Peptide
    Thymalin
    Outcome
    DecreaseThymalin-containing cell layer at older age
    Study

    humann: not reported in source

    Human epidermis and fetal reticuloepithelium
    Outcome group
    Aging markers · Skin and wound

    Source sentences

    Summary
    By the age of 70 years, the layer of thymalin-containing cells looks thinned and discontinuous.

    This result measures the body's own Thymalin. Nobody was given the peptide. It is not evidence about taking it.

  4. 04LabEndogenous levelEx vivo tissueOther

    In human epidermis, natural thymalin content decreased with age.

    In plain wordsIn lab tests, natural thymalin content in human skin decreased with age.

    Peptide
    Thymalin
    Outcome
    DecreaseAge-associated thymalin content
    Study

    humann: not reported in source

    Human epidermis and fetal reticuloepithelium
    Outcome group
    Aging markers · Skin and wound

    Source sentences

    Summary
    The content of thymalin, a thymic factor, decreases with age.

    This result measures the body's own Thymalin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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