In the MDA-MB-231 breast cancer cell line, thymosin beta4 was among the previously described genes isolated by a screen for genes highly expressed compared with normal MCF12A breast cells.
In plain wordsIn cancer cells, the cells' own thymosin beta4 gene was among genes found at high levels compared with normal breast cells.
- Peptide
- Thymosin beta-4 (human)
- Outcome
- IncreaseThymosin beta4 gene expression in breast cancer cells
- Study
humann: not reported in source
MDA-MB-231 breast cancer cell line versus MCF12A normal breast cell line- Comparator
- MCF12A normal breast cell line
- Outcome group
- Receptor activity and mechanism · Cancer
Source sentences
Sequence analysis revealed that 15 clones coded for previously described genes such as SNAP43, Cyr61, Thymosin beta4, tra1, elongation factor 1alpha, BSF-2/IL6, BiP, and GDP/GTP exchange protein.
1 context sentence(design, population, supporting numbers)
Differential screening of the library isolated 28 genes which by Northern analysis were highly expressed in the breast cancer cell line MDA-MB-231 compared to the normal breast cell line MCF12A.
This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.