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Study · Animal study (in vivo) · 2001

4 results

[Morphological features of the thymus in heliotrin hepatitis upon administration of immunostimulators].

Kasymova GG, Tukhtaev KR

Morfologiia (Saint Petersburg, Russia)1 Jan 2001

PMID12016764 (opens in a new tab)PepBankPUB-12016764

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In animals with heliotrin hepatitis, thymalin suppressed thymocyte destruction, but these parameters did not reach control levels.

    In plain wordsIn animals with heliotrin hepatitis, thymalin reduced thymus immune cell destruction, but the measured parameters did not reach control levels.

    Peptide
    Thymalin
    Outcome
    DecreaseThymocyte destruction
    Study

    n: not reported in source

    Heliotrin hepatitis
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Immunostimulants parandin and thymalin suppressed the extent of thymocyte destruction and stimulated their mitotic activity.
    1 context sentence
    Summary · context
    Although these parameters did not reach the control levels, the significant deceleration of hypoplastic processes in thymus, particularly in its cortex, were detected.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In animals with heliotrin hepatitis, thymalin stimulated thymocyte mitotic activity, but these parameters did not reach control levels.

    In plain wordsIn animals with heliotrin hepatitis, thymalin increased thymus immune cell division, but the measured parameters did not reach control levels.

    Peptide
    Thymalin
    Outcome
    IncreaseThymocyte mitotic activity
    Study

    n: not reported in source

    Heliotrin hepatitis
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Immunostimulants parandin and thymalin suppressed the extent of thymocyte destruction and stimulated their mitotic activity.
    1 context sentence
    Summary · context
    Although these parameters did not reach the control levels, the significant deceleration of hypoplastic processes in thymus, particularly in its cortex, were detected.

Studies that did not test the peptide alone2

In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymalin.

  1. 03AnimalNot a test of Thymalin aloneAnimal study (in vivo)Efficacy outcome

    In animals with heliotrin hepatitis, the immunostimulants, including thymalin, significantly slowed thymic hypoplasia, particularly in the cortex.

    In plain wordsIn animals with heliotrin hepatitis, the tested immunostimulants, including thymalin, slowed thymus tissue loss, especially in its outer region.

    Peptide
    Thymalin
    Outcome
    DecreaseThymic hypoplasia
    Study

    n: not reported in source

    Heliotrin hepatitis
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    Although these parameters did not reach the control levels, the significant deceleration of hypoplastic processes in thymus, particularly in its cortex, were detected.
    1 context sentence
    Summary · context
    Immunostimulants parandin and thymalin suppressed the extent of thymocyte destruction and stimulated their mitotic activity.

    In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymalin.

  2. 04AnimalNot a test of Thymalin aloneAnimal study (in vivo)Other

    In animals with heliotrin hepatitis, immunostimulant effects, including those of thymalin, did not depend on timing relative to heliotrin injection.

    In plain wordsIn animals with heliotrin hepatitis, the tested immunostimulants, including thymalin, acted independently of timing relative to heliotrin injection.

    Peptide
    Thymalin
    Outcome
    No significant changeDependence on administration timing
    Study

    n: not reported in source

    Heliotrin hepatitis
    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    Effect of immunostimulants was independent on the time of their administration in respect to heliotrin injection.
    1 context sentence
    Summary · context
    Immunostimulants parandin and thymalin suppressed the extent of thymocyte destruction and stimulated their mitotic activity.

    In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymalin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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