In the chick chorioallantoic membrane model, thymosin alpha‑1 enhanced angiogenesis.
In plain wordsIn chick embryo membranes, thymosin alpha‑1 increased the growth of new blood vessels.
- Peptide
- Thymosin alpha-1
- Outcome
- IncreaseAngiogenesis on chick chorioallantoic membrane
- Study
chickn: not reported in source
chick chorioallantoic membrane- Outcome group
- Angiogenesis · Cardiovascular
- Studied dose
- 0.016-6.66 nmoles per 10 microl aliquot · applied to the chorioallantoic membraneAs given in this study (chick).
Source sentences
Tbeta4, ProT(alpha) and T(alpha)1 were found to enhance angiogenesis
2 context sentences(design, population, supporting numbers)
The thymosin peptides tested were applied in 10 microl aliquots containing 0.01-4 nmoles of Tbeta4, Tbeta10 or Tbeta9, 0.016-6.66 nmoles of T(alpha)1, 4.1 pmoles-1.66 nmoles of ProT(alpha), and 4.4 pmoles-1.76 nmoles of ParaT(alpha).
The effect of alpha- and beta-thymosin peptides, namely prothymosin alpha (ProT(alpha)), thymosin alpha(1) (T(alpha)1), parathymosin alpha (ParaT(alpha)), thymosin beta(4) (Tbeta4), thymosin beta(10) (Tbeta10), and thymosin beta(9) (Tbeta9), on the angiogenesis process was investigated using the chi…