In the developing mouse mandible, cDNA subtraction identified thymosin beta4 as differentially expressed in the E12 mandible compared with the E10.5 mandible.
In plain wordsIn mouse embryos, the body's own thymosin beta4 gene was more active in the E12 jaw than in the E10.5 jaw.
- Peptide
- Thymosin beta-4 (human)
- Outcome
- IncreaseTbeta4 expression in E12 versus E10.5 mandible
- Study
mousen: not reported in source
Embryonic mouse mandible- Comparator
- E10.5 mandible
- Outcome group
- Gene expression · Musculoskeletal
Source sentences
By sequencing, homology search and semi-quantitative reverse transcription-polymerase chain reaction (RT-PCR), we thus found Pgk-1, Ccte, Hsp86, Nucleolin, Hsc73, Frg1, N-ras, Set alpha and Hsj2 from the E10.5 mandible, and E25, ATPase6, Mum2, Thymosin beta4 and L21 from the E12 mandible to be diffe…
1 context sentence(design, population, supporting numbers)
Based on the histological findings, we performed cDNA subtraction between the E10.5 and E12 mandibles to detect any differentially expressed genes which might be involved in the initiation of odontogenesis.
This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.