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Study · Observational study · n = 71 · 2000

8 results

End results in central precocious puberty with GnRH analog treatment: the data of the Italian Study Group for Physiopathology of Puberty.

Antoniazzi F, Arrigo T, Cisternino M, Galluzzi F, Bertelloni S, Pasquino AM, Borrelli P, Osio D, Mengarda F, De Luca F, Tatò L

Journal of pediatric endocrinology & metabolism : JPEM1 Jul 2000Cited by 20 (Europe PMC)

PMID10969920 (opens in a new tab)DOI10.1515/jpem.2000.13.s1.773 (opens in a new tab)PepBankPUB-10969920
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study8

8 results from studies that gave the peptide. 8 results from people.

  1. 01HumanObservational studyEfficacy outcome

    In girls with idiopathic central precocious puberty treated with triptorelin, 87.3% reached final height within the population norm.

    In plain wordsIn girls with early puberty treated with triptorelin, 87.3% reached final height within the population norm.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    Not applicableFinal height within population norm
    Study

    n = 71

    Outcome group
    Linear growth · Endocrine and hormones
    Studied dose
    Dose not stated

    Measurements

    Final height within population norm
    87.3%
    triptorelin cohort

    Source sentences

    Summary
    In a retrospective evaluation of the outcome in 71 girls with idiopathic CPP treated with triptorelin, we found that FH fell within the population norm and the target range in 87.3% and 90% of the patients respectively.
  2. 02HumanObservational studyEfficacy outcome

    In girls with idiopathic central precocious puberty treated with triptorelin, 90% reached final height within the target range.

    In plain wordsIn girls with early puberty treated with triptorelin, 90% reached final height within the target range.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    Not applicableFinal height within target range
    Study

    n = 71

    Outcome group
    Linear growth · Endocrine and hormones
    Studied dose
    Dose not stated

    Measurements

    Final height within target range
    90%
    triptorelin cohort

    Source sentences

    Summary
    In a retrospective evaluation of the outcome in 71 girls with idiopathic CPP treated with triptorelin, we found that FH fell within the population norm and the target range in 87.3% and 90% of the patients respectively.
  3. 03HumanObservational studyEfficacy outcome

    In girls with central precocious puberty, triptorelin arrested pubertal development.

    In plain wordsIn girls with early puberty, triptorelin treatment was linked to arrest of pubertal development.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    DecreasePubertal arrest
    Study

    n: not reported in source

    Outcome group
    Linear growth · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Both GnRHa administration modes were effective in arresting pubertal development and all girls had complete recovery of the reproductive axis after therapy.
    1 context sentence
    Summary · context
    Study L Growth data were analyzed of three groups of patients: treated with i.n. spray buserelin, i.m. triptorelin and untreated.
  4. 04HumanObservational studyEfficacy outcome

    All girls recovered reproductive-axis function after triptorelin therapy for central precocious puberty.

    In plain wordsAll girls recovered reproductive hormone function after triptorelin treatment for early puberty.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    Not applicableRecovery of reproductive axis
    Study

    n: not reported in source

    Outcome group
    Linear growth · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Both GnRHa administration modes were effective in arresting pubertal development and all girls had complete recovery of the reproductive axis after therapy.
    1 context sentence
    Summary · context
    Study L Growth data were analyzed of three groups of patients: treated with i.n. spray buserelin, i.m. triptorelin and untreated.
  5. 05HumanObservational studyEfficacy outcome

    In patients with central precocious puberty, triptorelin improved final height compared with untreated patients.

    In plain wordsIn patients with early puberty, triptorelin treatment was linked to greater final height than in untreated patients.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    IncreaseFinal height versus untreated patients
    Study

    n: not reported in source

    Comparator
    Untreated patients
    Outcome group
    Linear growth · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Treated patients showed an improvement in final height in comparison with untreated patients and compared to predicted height at the start of treatment with both agonist treatments.
    1 context sentence
    Summary · context
    Study L Growth data were analyzed of three groups of patients: treated with i.n. spray buserelin, i.m. triptorelin and untreated.
  6. 06HumanObservational studyEfficacy outcome

    In patients with central precocious puberty, final height after triptorelin exceeded the initial prediction.

    In plain wordsIn patients with early puberty, final height after triptorelin exceeded the initial prediction.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    IncreaseFinal height versus initial prediction
    Study

    n: not reported in source

    Comparator
    Predicted height at treatment start
    Outcome group
    Linear growth · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Treated patients showed an improvement in final height in comparison with untreated patients and compared to predicted height at the start of treatment with both agonist treatments.
    1 context sentence
    Summary · context
    Study L Growth data were analyzed of three groups of patients: treated with i.n. spray buserelin, i.m. triptorelin and untreated.
  7. 07HumanObservational studyEfficacy outcome

    In central precocious puberty, long-acting triptorelin produced greater adult-height improvement than intranasal buserelin.

    In plain wordsIn early puberty, long-acting triptorelin was linked to greater adult-height improvement than intranasal buserelin.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    IncreaseAdult-height improvement versus buserelin
    Study

    n: not reported in source

    Comparator
    Intranasal buserelin
    Outcome group
    Linear growth · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    However, patients treated with the long-acting slow release preparation had a better improvement in adult height and reached or exceeded the genetic height potential.
    1 context sentence
    Summary · context
    Study L Growth data were analyzed of three groups of patients: treated with i.n. spray buserelin, i.m. triptorelin and untreated.
  8. 08HumanObservational studyEfficacy outcome

    In central precocious puberty, patients receiving long-acting triptorelin reached or exceeded genetic height potential.

    In plain wordsIn early puberty, patients receiving long-acting triptorelin reached or exceeded their genetic height potential.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    Not applicableGenetic height potential
    Study

    n: not reported in source

    Outcome group
    Linear growth · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    However, patients treated with the long-acting slow release preparation had a better improvement in adult height and reached or exceeded the genetic height potential.
    1 context sentence
    Summary · context
    Study L Growth data were analyzed of three groups of patients: treated with i.n. spray buserelin, i.m. triptorelin and untreated.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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