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Study · Measured the body's own peptide · 2000

2 results

Sequestered actin in chick embryo fibroblasts.

Nagamalleswari K, Safer D

Molecular and cellular biochemistry1 Jun 2000Cited by 4 (Europe PMC)

PMID10942202 (opens in a new tab)DOI10.1023/a:1007025602110 (opens in a new tab)PepBankPUB-10942202
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelIn vitro (cells)Other

    In chick embryo fibroblast extracts, most G-actin was detected as a complex with the cells' own Tbeta4.

    In plain wordsIn chick cells, most of the cells' own free actin was bound to the cells' own thymosin beta4.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableG-actin complexed with Tbeta4 in fibroblast extracts
    Study

    chickenn: not reported in source

    chick embryo fibroblast extracts
    Outcome group
    Receptor activity and mechanism · Whole body

    Source sentences

    Summary
    Fibroblast extracts are analyzed by non-denaturing polyacrylamide gel electrophoresis and immunoblotting where most of the G-actin is detected as a complex with Tbeta4.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  2. 02LabEndogenous levelIn vitro (cells)Other

    In chick embryo fibroblast extracts, most G-actin eluted in a peak that also contained the cells' own Tbeta4 at an overall molar ratio of 1.9:1 relative to actin.

    In plain wordsIn chick cells, the cells' own thymosin beta4 was present at about 1.9 parts per part of actin in the main actin peak.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableTbeta4 to actin molar ratio in gel filtration peak
    Study

    chickenn: not reported in source

    chick embryo fibroblast extracts
    Outcome group
    Receptor activity and mechanism · Whole body

    Measurements

    Tbeta4 to actin molar ratio
    1.9 :1
    gel filtration actin peak

    Source sentences

    Summary
    When fibroblast extracts are fractionated by gel filtration and the fractions are analyzed by PAGE and HPLC, most of the G-actin elutes in a peak that also contains Tbeta4 at an overall molar ratio of 1.9:1 relative to actin.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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