In conscious dogs, coadministration of gamma-hydroxybutyric acid did not modify the GH response to hexarelin, which was used as a GH stimulus.
In plain wordsIn dogs, gamma-hydroxybutyric acid did not change the growth hormone response to hexarelin.
- Peptide
- Hexarelin
- Outcome
- No significant changeGH response to hexarelin with gamma-hydroxybutyric acid coadministration
- Study
dogn: not reported in source
- Comparator
- Hexarelin alone
- Outcome group
- Growth hormone and IGF-1 · Endocrine and hormones
Source sentences
In this species, growth hormone response to hexarelin (31.25 microg/kg, IV), a potent growth hormone-releasing peptide, was not modified by coadministration of gamma-hydroxybutyric acid (50 mg/kg, IV).
1 context sentence(design, population, supporting numbers)
In conscious dogs, gamma-hydroxybutyric acid (20 and 50 mg/kg, IV) and baclofen (0.15, 0.30 mg/kg, IV) also were ineffective in stimulating growth hormone secretion.
In this study, Hexarelin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Hexarelin.