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Study · Non-randomized trial · n = 8 · 2000

1 result

Hemodynamic effects of acute hyperglycemia in type 2 diabetic patients.

Marfella R, Nappo F, De Angelis L, Paolisso G, Tagliamonte MR, Giugliano D

Diabetes care1 May 2000Cited by 77 (Europe PMC)

PMID10834426 (opens in a new tab)DOI10.2337/diacare.23.5.658 (opens in a new tab)PepBankPUB-10834426
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. 1 result from people.

  1. 01HumanNon-randomized trialEfficacy outcome

    In patients with type 2 diabetes, glutathione completely prevented the vascular effects of hyperglycemia.

    In plain wordsIn patients with type 2 diabetes, glutathione prevented the vascular effects of high glucose.

    Peptide
    Glutathione
    Outcome
    DecreaseVascular effects of hyperglycemia
    Study

    n = 8

    Outcome group
    Blood pressure · Cardiovascular
    Studied dose
    600 mg bolus followed by 5 mg/min infusion · intravenousAs given in this study (human).

    Source sentences

    Summary
    Glutathione, a free radical scavenger, completely prevented the vascular effects of hyperglycemia.
    2 context sentences
    Summary · context
    Twenty newly diagnosed complication-free diet-treated type 2 diabetic patients participated in the study.
    Summary · context
    A group of 8 patients also underwent a glutathione infusion (600 mg as an intravenous bolus followed by 5 mg/min infusion) during the clamp.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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